@article{Mungroo_M-2020_176522,
title = {Novel Coronavirus: Current Understanding of Clinical Features, Diagnosis, Pathogenesis, and Treatment Options},
author = {Mungroo, M. and Khan, N. and Siddiqui, R.},
month = {apr},
year = {2020},
abstract = {Since December 2019, coronavirus disease 2019 (COVID-19) caused by severe acuterespiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in devastating consequencesworldwide and infected more than 350,000 individuals and killed more than 16,000 people.SARS-CoV-2 is the seventh member of the coronavirus family to affect humans. Symptoms ofCOVID-19 include fever (88%), cough (68%), vomiting (5%) and diarrhoea (3.7%), and transmissionof SARS-CoV-2 is thought to occur from human to human via respiratory secretions released by theinfected individuals when coughing and sneezing. COVID-19 can be detected through computedtomography scans and confirmed through molecular diagnostics tools such as polymerase chainreaction. Currently, there are no effective treatments against SARS-CoV-2, hence antiviral drugshave been used to reduce the development of respiratory complications by reducing viral load.The purpose of this review is to provide a comprehensive update on the pathogenesis, clinical aspects,diagnosis, challenges and treatment of SARS-CoV-2 infections.},
volume = {9},
issue = {4},
journal = {Pathogens},
publisher = {MDPI},
url = {https://doi.org/10.3390/pathogens9040297},
}
