TY - JOUR
AU - Berry, Colin
AU - Lomholt-Welch, Harriet
AU - Morrow, Andrew J.
AU - Sykes, Robert
AU - Saleh, Merna
AU - Zahra, Baryab
AU - MacIntosh, Alasdair
AU - Kamdar, Anna
AU - Bagot, Catherine
AU - Bayes, Hannah K.
AU - Blyth, Kevin G.
AU - Bulluck, Heeraj
AU - Carrick, David
AU - Church, Colin
AU - Corcoran, David
AU - Findlay, Iain
AU - Gibson, Vivienne B.
AU - Gillespie, Lynsey
AU - Grieve, Douglas
AU - Barrientos, Pauline Hall
AU - Ho, Antonia
AU - Lang, Ninian N.
AU - Lowe, David J.
AU - Lennie, Vera
AU - Macfarlane, Peter W.
AU - Mayne, Kaitlin J.
AU - Mark, Patrick B.
AU - McConnachie, Alex
AU - McGeoch, Ross
AU - Nordin, Sabrina
AU - Payne, Alexander
AU - Rankin, Alastair J.
AU - Robertson, Keith E.
AU - Ryan, Nicola
AU - Roditi, Giles
AU - Sattar, Naveed
AU - Stobo, David
AU - Touyz, Rhian M.
AU - Veldtman, Gruschen
AU - Weeden, Sarah
AU - Weir, Robin A.
AU - Watkins, Stuart
AU - Welsh, Paul
AU - Mangion, Kenneth
AU - Allwood-Spiers, Sarah
PY - 2023
DA - November
TI - Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study
JO - Heart and Mind
EP - 245
VL - 7
IS - 4
DO - https://doi.org/10.4103/hm.HM-D-23-00037
AB - Background: The multisystem associations between baseline mental health status and coronavirus disease-19 (COVID)-19 illness trajectory are uncertain. Objectives: This article will investigate the associations between baseline mental health status and disease trajectory following COVID-19 hospitalization, which may have implications for practice and future research. Methods: The Chief Scientist Office Cardiovascular and Pulmonary Imaging in severe acute respiratory syndrome (SARS) COVID-19 study is a prospective, observational, multicenter, longitudinal, secondary care cohort study that assessed the time-course of multi-organ injury in posthospital survivors of COVID-19. Patients were assessed in-hospital, at 28–60 days after discharge and in the longer term using electronic health record linkage. Results: One hundred and fifty-two patients (mean ± standard deviation [SD] age 54.3 ± 11.8 years, 43% female, 40% most socio-economically deprived quintile, 33% history of mental health history) were enrolled and had mental health serially assessed using the Patient Health Questionnaire-4 (PHQ-4) questionnaire. Fifty-three (35%) had PHQ-4 score of 6–12 consistent with moderate-severe symptoms of anxiety or depression and this was associated with diagnostic criteria for myocarditis (P = 0.0498). Moderate-severe symptoms of anxiety or depression were positively associated with higher perception of illness, lower health-related quality of life (HRQoL), and poorer physical function. The mean (SD) duration of follow-up after hospital discharge was 428 (86) days (range, 290–627 days). PHQ-4 score was not associated with clinical outcomes at follow-up. Conclusions: In patients who have been hospitalized with COVID-19, moderate-severe symptoms of anxiety or depression were associated with myocarditis, worse HRQoL, higher perception of illness, and lower levels of physical function.
PB - Wolters Kluwer
UR - https://eprints.gla.ac.uk/321139/
KW - Coronavirus (COVID-19)
KW - Mental health and wellbeing
KW - Hospital care
ER