TY - JOUR
AU - Gharibzadeh, Safoora
AU - Routen, Ash
AU - Razieh, Cameron
AU - Zaccardi, Francesco
AU - Lawson, Claire A.
AU - Gillies, Clare L.
AU - Heller, Simon
AU - Davies, Melanie J.
AU - Atkins, Helen
AU - Bain, Stephen C
AU - Lone, Nazir L
AU - Poinasamy, Krisnah
AU - Peto, Tunde
AU - Robertson, Elizabeth
AU - Young, Bob
AU - Johnston, Desmond
AU - Quint, Jennifer K.
AU - Valabhji, Jonathan
AU - Ismail, Khalida
AU - Marks, Michael
AU - Horsley, Alex
AU - Docherty, Annemarie B.
AU - Harrison, Ewen M.
AU - Chalmers, James D.
AU - Ho, Ling-Pei
AU - Raman, Betty
AU - Brightling, Chris
AU - Elneima, Omer
AU - Evans, Rachel
AU - Greening, Neil J.
AU - Harris, Victoria C
AU - Houchen-Wolloff, Linzy
AU - Sereno, Marco
AU - Shikotra, Aarti
AU - Singapuri, Amisha
AU - Wain, Louise V.
AU - Langenberg, Claudia
AU - Dennis, John
AU - Petrie, John
AU - Sattar, Naveed
AU - Leavy, Olivia C.
AU - Richardson, Mattew
AU - Saunders, Ruth M.
AU - McArdle, Anne
AU - McASuley, Hamish
AU - Yates, Tom A.
AU - Khunti, Kamlesh
PY - 2024
DA - December
TI - Long term health outcomes in people with diabetes 12 months after hospitalisation with COVID-19 in the UK: a prospective cohort study
JO - eClinicalMedicine
VL - 79
DO - http://dx.doi.org/10.1016/j.eclinm.2024.103005
AB - Background: People with diabetes are at increased risk of hospitalisation, morbidity, and mortality following SARS-CoV-2 infection. Long-term outcomes for people with diabetes previously hospitalised with COVID-19 are, however, unknown. This study aimed to determine the longer-term physical and mental health effects of COVID-19 in people with and without diabetes. Methods: The PHOSP-COVID study is a multicentre, long-term follow-up study of adults discharged from hospital between 1 February 2020 and 31 March 2021 in the UK following COVID-19, involving detailed assessment at 5 and 12 months after discharge. The association between diabetes status and outcomes were explored using multivariable linear and logistic regressions. Findings: People with diabetes who survived hospital admission with COVID-19 display worse physical outcomes compared to those without diabetes at 5- and 12-month follow-up. People with diabetes displayed higher fatigue (only at 5 months), frailty, lower physical performance, and health-related quality of life and poorer cognitive function. Differences in outcomes between diabetes status groups were largely consistent from 5 to 12-months. In regression models, differences at 5 and 12 months were attenuated after adjustment for BMI and presence of other long-term conditions. Interpretation: People with diabetes reported worse physical outcomes up to 12 months after hospital discharge with COVID-19 compared to those without diabetes. These data support the need to reduce inequalities in long-term physical and mental health effects of SARS-CoV-2 infection in people with diabetes.
PB - Elsevier
UR - https://eprints.gla.ac.uk/346841/
KW - Coronavirus (COVID-19)
KW - Hospital care
ER