TY - DATA
AU - Candido, Darlan S.
AU - Claro, Ingra M.
AU - de Jesus, Jaqueline G.
AU - Souza, William M.
AU - Moreira, Filipe R. R.
AU - Dellicour, Simon
AU - Mellan, Thomas A.
AU - du Plessis, Louis
AU - Pereira, Rafael H. M.
AU - Sales, Flavia C. S.
AU - Manuli, Erika R.
AU - Thézé, Julien
AU - Almeida, Luiz
AU - Menezes, Mariane T.
AU - Voloch, Carolina M.
AU - Fumagalli, Marcilio J.
AU - Coletti, Thaís M.
AU - Da Silva, Camila A. M.
AU - Ramundo, Mariana S.
AU - Amorim, Mariene R.
AU - Hoeltgebaum, Henrique H.
AU - Mishra, Swapnil
AU - Gill, Mandev S.
AU - Carvalho, Luiz M.
AU - Buss, Lewis F.
AU - Prete, Carlos A.
AU - Ashworth, Jordan
AU - Nakaya, Helder I.
AU - Peixoto, Pedro S.
AU - Brady, Oliver J.
AU - Nicholls, Samuel M.
AU - Tanuri, Amilcar
AU - Rossi, Átila D.
AU - Braga, Carlos K.V.
AU - Gerber, Alexandra L.
AU - de C. Guimarães, Ana Paula
AU - Gaburo, Nelson
AU - Alencar, Cecila Salete
AU - Ferreira, Alessandro C.S.
AU - Lima, Cristiano X.
AU - Levi, José Eduardo
AU - Granato, Celso
AU - Ferreira, Giulia M.
AU - Francisco, Ronaldo S.
AU - Granja, Fabiana
AU - Garcia, Marcia T.
AU - Moretti, Maria Luiza
AU - Perroud, Mauricio W.
AU - Castiñeiras, Terezinha M. P. P.
AU - Lazari, Carolina S.
AU - Hill, Sarah C.
AU - de Souza Santos, Andreza Aruska
AU - Simeoni, Camila L.
AU - Forato, Julia
AU - Sposito, Andrei C.
AU - Schreiber, Angelica Z.
AU - Santos, Magnun N. N.
AU - de Sá, Camila Zolini
AU - Souza, Renan P.
AU - Resende-Moreira, Luciana C.
AU - Teixeira, Mauro M.
AU - Hubner, Josy
AU - Leme, Patricia A. F.
AU - Moreira, Rennan G
AU - Nogueira, Maurício L.
AU - Ferguson, Neil M
AU - Costa, Silvia F.
AU - Proenca-Modena, José Luiz
AU - Vasconcelos, Ana Tereza R.
AU - Bhatt, Samir
AU - Lemey, Philippe
AU - Wu, Chieh-Hsi
AU - Rambaut, Andrew
AU - Loman, Nick J.
AU - Aguiar, Renato S.
AU - Pybus, Oliver G.
AU - Sabino, Ester C.
AU - Faria, Nuno R.
PY - 2020
DA - August
TI - Data from: Evolution and epidemic spread of SARS-CoV-2 in Brazil
DO - https://doi.org/10.5061/dryad.rxwdbrv5z
AB - Brazil currently has one of the fastest growing SARS-CoV-2 epidemics in the world. Owing to limited available data, assessments of the impact of non-pharmaceutical interventions (NPIs) on virus spread remain challenging. Using a mobility-driven transmission model, we show that NPIs reduced the reproduction number from &gt;3 to 1–1.6 in São Paulo and Rio de Janeiro. Sequencing of 427 new genomes and analysis of a geographically representative genomic dataset identified &gt;100 international virus introductions in Brazil. We estimate that most (76%) of the Brazilian strains fell in three clades that were introduced from Europe between 22 February11 March 2020. During the early epidemic phase, we found that SARS-CoV-2 spread mostly locally and within-state borders. After this period, despite sharp decreases in air travel, we estimated multiple exportations from large urban centers that coincided with a 25% increase in average travelled distances in national flights. This study sheds new light on the epidemic transmission and evolutionary trajectories of SARS-CoV-2 lineages in Brazil, and provide evidence that current interventions remain insufficient to keep virus transmission under control in the country.
PB - Dryad
UR - https://www.research.ed.ac.uk/en/datasets/ed8d1a96-170e-4548-b778-22d86007fb7f
KW - Coronavirus (COVID-19)
ER