TY - JOUR
AU - Nguyen, Bach Tran
AU - Bertrand, Julie
AU - Zhang, Shengyuan
AU - Yu, Ly-Mee
AU - Harris, Victoria Claire
AU - Little, Paul
AU - Breuer, Judith
AU - Guedj, Jérémie
AU - PANORAMIC study group
AU - Agyeman, Akosua A.
AU - Butler, Christopher C.
AU - Lowe, David M.
AU - Standing, Joseph F.
PY - 2025
DA - April
TI - A viro-immunological model to characterize the antiviral effect of molnupiravir in SARS-CoV-2-infected outpatients: implication for treatment duration
JO - Journal of Infectious Diseases
EP - e1090
VL - 231
IS - 6
DO - https://doi.org/10.1093/infdis/jiaf158
AB - BackgroundThe antiviral efficacy of molnupiravir against SARS-CoV-2 is controversial. Here, we develop a model integrating viral and immune dynamics to characterize the mechanism of action of molnupiravir in vivo and its impact on viral dynamics during and after treatment.
PB - Oxford University Press
UR - https://hdl.handle.net/10023/32540
KW - Coronavirus (COVID-19)
ER