@article{Relph_K-2022_84605,
title = {Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission},
author = {Relph, K. and Russell, C. and Fairfield, C. and Turtle, L. and de Silva, T. and Siggins, M. and Drake, T. and Thwaites, R. and Abrams, S. and Moore, S. and Hardwick, H. and Oosthuyzen, W. and Harrison, E. and Docherty, A. and Openshaw, P. and Baillie, J. and Semple, M. and Ho, A. and ISARIC4C Investigators},
month = {may},
year = {2022},
abstract = {Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium World Health Organization Clinical Characterisation Protocol UK study). Although procalcitonin was higher in bacterial coinfection, this was neither clinically significant (median [IQR], 0.33 [0.11–1.70] ng/mL vs 0.24 [0.10–0.90] ng/mL) nor diagnostically useful (area under the receiver operating characteristic curve, 0.56 [95% confidence interval, .51–.60]).},
volume = {9},
issue = {5},
journal = {Open Forum Infectious Diseases},
publisher = {Oxford University Press},
url = {https://doi.org/10.1093/ofid/ofac179},
}
