@article{Thakur_A-2023_138792,
title = {Single-Cell Transcriptomics Reveals Evidence of Endothelial Dysfunction in the Brains of COVID-19 Patients with Implications for Glioblastoma Progression},
author = {Thakur, A. and Liang, L. and Banerjee, S. and Zhang, K.},
month = {may},
year = {2023},
abstract = {Background: Endothelial dysfunction is implicated in various inflammatory diseases such as ischemic stroke, heart attack, organ failure, and COVID-19. Recent studies have shown that endothelial dysfunction in the brain is attributed to excessive inflammatory responses caused by the SARS-CoV-2 infection, leading to increased permeability of the blood-brain barrier and consequently neurological damage. Here, we aim to examine the single-cell transcriptomic landscape of endothelial dysfunction in COVID-19 and its implications for glioblastoma (GBM) progression.},
volume = {13},
issue = {5},
journal = {Brain Sciences},
publisher = {MDPI},
url = {https://doi.org/10.3390/brainsci13050762},
}
