@article{Mutambudzi_M-2020_15094, title = {Occupation and risk of severe COVID-19: prospective cohort study of 120 075 UK Biobank participants}, author = {Mutambudzi, M. and Niedzwiedz, C. and Macdonald, E. and Leyland, A. and Mair, F. and Anderson, J. and Celis-Morales, C. and Cleland, J. and Forbes, J. and Gill, J. and Hastie, C. and Ho, F. and Jani, B. and Mackay, D. and Nicholl, B. and O'Donnell, C. and Sattar, N. and Welsh, P. and Pell, J. and Katikireddi, S. and Demou, E.}, month = {dec}, year = {2020}, abstract = {Objectives: To investigate severe COVID-19 risk by occupational group. Methods: Baseline UK Biobank data (2006–10) for England were linked to SARS-CoV-2 test results from Public Health England (16 March to 26 July 2020). Included participants were employed or self-employed at baseline, alive and aged <65 years in 2020. Poisson regression models were adjusted sequentially for baseline demographic, socioeconomic, work-related, health, and lifestyle-related risk factors to assess risk ratios (RRs) for testing positive in hospital or death due to COVID-19 by three occupational classification schemes (including Standard Occupation Classification (SOC) 2000). Results: Of 120 075 participants, 271 had severe COVID-19. Relative to non-essential workers, healthcare workers (RR 7.43, 95% CI 5.52 to 10.00), social and education workers (RR 1.84, 95% CI 1.21 to 2.82) and other essential workers (RR 1.60, 95% CI 1.05 to 2.45) had a higher risk of severe COVID-19. Using more detailed groupings, medical support staff (RR 8.70, 95% CI 4.87 to 15.55), social care (RR 2.46, 95% CI 1.47 to 4.14) and transport workers (RR 2.20, 95% CI 1.21 to 4.00) had the highest risk within the broader groups. Compared with white non-essential workers, non-white non-essential workers had a higher risk (RR 3.27, 95% CI 1.90 to 5.62) and non-white essential workers had the highest risk (RR 8.34, 95% CI 5.17 to 13.47). Using SOC 2000 major groups, associate professional and technical occupations, personal service occupations and plant and machine operatives had a higher risk, compared with managers and senior officials. Conclusions: Essential workers have a higher risk of severe COVID-19. These findings underscore the need for national and organisational policies and practices that protect and support workers with an elevated risk of severe COVID-19.}, pages = {307-314}, volume = {78}, issue = {5}, journal = {Occupational and Environmental Medicine}, publisher = {BMJ Publishing Group}, url = {http://dx.doi.org/10.1136/oemed-2020-106731}, }