@article{Farouq_M-2021_27095,
title = {Biomolecular interactions with nanoparticles : applications for COVID-19},
author = {Farouq, M. and Al Qaraghuli, M. and Kubiak-Ossowska, K. and Ferro, V. and Mulheran, P.},
month = {apr},
year = {2021},
abstract = {Nanoparticles are small particles sized 1–100 nm, which have a large surface-to-volume ratio, allowing efficient adsorption of drugs, proteins, and other chemical compounds. Consequently, functionalized nanoparticles have potential diagnostic and therapeutic applications. A variety of nanoparticles have been studied, including those constructed from inorganic materials, biopolymers, and lipids. In this review, we focus on recent work targeting the severe acute respiratory syndrome coronavirus 2 virus that causes coronavirus disease (COVID-19). Understanding the interactions between coronavirus-specific proteins (such as the spike protein and its host cell receptor angiotensin-converting enzyme 2) with different nanoparticles paves the way to the development of new therapeutics and diagnostics that are urgently needed for the fight against COVID-19, and indeed for related future viral threats that may emerge.},
volume = {54},
journal = {Current Opinion in Colloid & Interface Science},
publisher = {Elsevier},
url = {https://doi.org/10.1016/j.cocis.2021.101461},
}
