@article{Al-Jarallah_M-2021_27101,
title = {In-hospital mortality in SARS-CoV-2 stratified by hemoglobin levels : a retrospective study},
author = {Al-Jarallah, M. and Rajan, R. and Al Saber, A. and Pan, J. and TAl-Sultan, A. and Abdelnaby, H. and Alroomi, M. and Dashti, R. and Aboelhassan, W. and Almutairi, F. and Abdullah, M. and Alotaibi, N. and Al Saleh, M. and AlNasrallah, N. and Al-Bader, B. and Malhas, H. and Ramadhan, M. and Hamza, M. and Zhanna, K.},
month = {may},
year = {2021},
abstract = {This study is to estimate in-hospital mortality in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients stratified by hemoglobin (Hb) level. Patients were stratified according to hemoglobin level into two groups, that is, Hb &lt;100 g/L and Hb &gt;100 g/L. A total of 6931 patients were included. Of these, 6377 (92%) patients had hemoglobin levels &gt;100 g/L. The mean age was 44 ± 17 years, and 66% of the patients were males. The median length of overall hospital stay was 13 days [2; 31]. The remaining 554 (8%) patients had a hemoglobin level &lt;100 g/L. Overall mortality was 176 patients (2.54%) but was significantly higher in the group with hemoglobin levels &lt;100 g/L (124, 22.4%) than in the group with hemoglobin levels &gt;100 g/L (52, 0.82%). Risk factors associated with increased mortality were determined by multi- variate analysis. The Kaplan-Meier survival analysis showed hemoglobin as a predictor of mortality. Cox proportional hazards regression coefficients for hemoglobin for the HB ≤ 100 category of hemoglobin were significant, B = 2.79, SE = 0.17, and HR = 16.34, p &lt; 0.001. Multivariate logistic regression showed Hb &lt; 100 g/L had a higher cumu- lative all-cause in-hospital mortality (22.4% vs. 0.8%; adjusted odds ratio [aOR], 0.33; 95% [CI]: [0.20–0.55]; p &lt; 0.001). In this study, hemoglobin levels &lt;100 g/L were found to be an independent predictor of in-hospital mortality.},
pages = {857-1016},
volume = {193},
issue = {5},
journal = {eJHaem},
publisher = {British Society for Haematology  and Wiley},
url = {https://doi.org/10.1002/jha2.195},
}
