@article{McGovern_J-2021_41673,
title = {Relation between body composition, systemic inflammatory response, and clinical outcomes in patients admitted to an urban teaching hospital with COVID-19},
author = {McGovern, J. and Dolan, R. and Richards, C. and Laird, B. and McMillan, D. and Maguire, D.},
month = {aug},
year = {2021},
abstract = {Background: COVID-19 has been associated with cases of severe respiratory illness, admissions to intensive therapy units (ITUs), and high mortality rates. Objectives: The aim of the present study was to examine the relation between computed tomography- body composition (CT-BC) measurements, systemic inflammation, and clinical outcomes in those with COVID-19. Methods: Patients who presented to our institution between March 17 and May 1, 2020, with a positive PCR test for COVID-19 or characteristic radiological changes, were assessed for inclusion. Data collected included general demographic details, clinicopathological variables, poGPS, NLR , CT-BC measurements, and clinical outcomes including ITU admission and 30-d mortality, of those admitted. Results: Sixty-three patients met the study inclusion criteria. Forty-two patients (67%) were aged ≥70 y, 30 (47.6%) were male and 34.9% ( n = 22) had a poGPS ≥1. ITU admission was significantly associated with a high VFA ( P &lt; 0.05). Thirty-day mortality was associated with high VFA (P &lt; 0.05) and low SMI (P &lt; 0.05). Conclusions: Sarcopenia in the presence of obesity was associated with clinical outcomes including greater 30-d mortality.},
pages = {2236-2244},
volume = {151},
issue = {8},
journal = {Journal of Nutrition},
publisher = {Oxford University Press},
url = {https://doi.org/10.1093/jn/nxab142},
}
