@article{Manship_T-2022_57970,
title = {Effect of COVID-19 on presentations of decompensated liver disease in Scotland},
author = {Manship, T. and Brennan, P. and Campbell, I. and Campbell, S. and Clouston, T. and Dillon, J. and Forrest, E. and Fraser, A. and Goh, T. and Johnston, M. and Khan, M. and Livie, V. and Murray, I. and Saunders, J. and Troland, D. and Simpson, K.},
month = {jan},
year = {2022},
abstract = {Background and aims: SARS-CoV-2 and consequent pandemic has presented unique challenges. Beyond the direct COVID-related mortality in those with liver disease, we sought to determine the effect of lockdown on people with liver disease in Scotland. The effect of lockdown on those with alcohol-related disease is of interest; and whether there were associated implications for a change in alcohol intake and consequent presentations with decompensated disease. Methods: We performed a retrospective analysis of patients admitted to seven Scottish hospitals with a history of liver disease between 1 April and 30 April 2020 and compared across the same time in 2017, 2018 and 2019. We also repeated an intermediate assessment based on a single centre to examine for delayed effects between 1 April and 31 July 2020. Results: We found that results and outcomes for patients admitted in 2020 were similar to those in previous years in terms of morbidity, mortality, and length of stay. In the Scotland-wide cohort: admission MELD (Model for End-stage Liver Disease) (16 (12–22) vs 15 (12–19); p=0.141), inpatient mortality ((10.9% vs 8.6%); p=0.499) and length of stay (8 days (4–15) vs 7 days (4–13); p=0.140). In the Edinburgh cohort: admission MELD (17 (12–23) vs 17 (13–21); p=0.805), inpatient mortality ((13.7% vs 10.1%; p=0.373) and length of stay (7 days (4–14) vs 7 days (3.5–14); p=0.525)). Conclusion: This assessment of immediate and medium-term lockdown impacts on those with chronic liver disease suggested a minimal effect on the presentation of decompensated liver disease to secondary care.},
volume = {9},
issue = {1},
journal = {BMJ Open Gastroenterology},
publisher = {BMJ Publishing Group},
url = {https://doi.org/10.1136/bmjgast-2021-000795},
}
