@article{Nelson_C-2020_6680,
title = {Genetic associations with plasma angiotensin converting enzyme 2 concentration: Potential relevance to COVID-19 risk},
author = {Nelson, C. and Sama, I. and Codd, V. and Webb, T. and Ye, S. and Lang, C. and Voors, A. and Ng, L. and Samani, N.},
month = {sep},
year = {2020},
abstract = {Male sex has emerged as a major independent risk factor for severe disease and death from severe acute respiratory syndrome coronavirus–related coronavirus disease 2019 (COVID-19).Severe acute respiratory syndrome coronavirus 2 infects cells via the angiotensin converting enzyme 2 (ACE2) receptor, a widely distributed cell-surface receptor.In 2 cohorts of patients with heart failure (BIOSTAT-CHF [Biology Study to Tailored Treatment in Chronic Heart Failure]), we recently showed that age-adjusted plasma concentrations of ACE2 are higher in men than in women.},
pages = {1117-1119},
volume = {142},
issue = {11},
journal = {Circulation},
publisher = {American Heart Association},
url = {https://doi.org/10.1161/CIRCULATIONAHA.120.049007},
}
