@article{Pascall_D-2022_83302,
title = {The SARS-CoV-2 Alpha variant caused increased clinical severity of disease in Scotland: a genomics-based prospective cohort analysis},
author = {Pascall, D. and Mollett, G. and Vink, E. and Shepherd, J. and Williams, T. and Wastnedge, E. and Blacow, R. and Hughes, J. and Robertson, D. and Lycett, S. and Bulteel, N. and Campbell, R. and Campbell, A. and Clifford, S. and Davis, C. and da Silva Filipe, A. and Fjodorova, L. and Forrest, R. and Goldstein, E. and Gunson, R. and Haughney, J. and Holden, M. and Honour, P. and James, E. and Lewis, T. and McHugh, M. and Onishi, Y. and Parcell, B. and Sakka, N. and Shabaan, S. and Smollett, K. and Templeton, K. and The COVID-19 Genomics UK (COG-UK) Consortium and Thomson, E.},
month = {feb},
year = {2022},
abstract = {BackgroundThe SARS-CoV-2 Alpha variant was associated with increased transmission relative to other variants present at the time of its emergence and several studies have shown an association between Alpha variant infection and increased hospitalisation and 28-day mortality. However, none have addressed the impact on maximum severity of illness in the general population classified by the level of respiratory support required, or death.},
journal = {MedRxiv},
publisher = {medRxiv},
url = {https://doi.org/10.1101/2021.08.17.21260128},
}
