@article{Sera_F-2021_93087, title = {A cross-sectional analysis of meteorological factors and SARS-CoV-2 transmission in 409 cities across 26 countries}, author = {Sera, F. and Armstrong, B. and Abbott, S. and Meakin, S. and O'Reilly, K. and von Borries, R. and Schneider, R. and Royé, D. and Hashizume, M. and Pascal, M. and Tobias, A. and Vicedo-Cabrera, A. and MCC Collaborative Research Network and CMMID COVID-19 Working Group and Gasparrini, A. and Lowe, R.}, month = {oct}, year = {2021}, abstract = {There is conflicting evidence on the influence of weather on COVID-19 transmission. Our aim is to estimate weather-dependent signatures in the early phase of the pandemic, while controlling for socio-economic factors and non-pharmaceutical interventions. We identify a modest non-linear association between mean temperature and the effective reproduction number (Re) in 409 cities in 26 countries, with a decrease of 0.087 (95% CI: 0.025; 0.148) for a 10 °C increase. Early interventions have a greater effect on Rewith a decrease of 0.285 (95% CI 0.223; 0.347) for a 5th - 95th percentile increase in the government response index. The variation in the effective reproduction number explained by government interventions is 6 times greater than for mean temperature. We find little evidence of meteorological conditions having influenced the early stages of local epidemics and conclude that population behaviour and government interventions are more important drivers of transmission.}, volume = {12}, issue = {1}, journal = {Nature Communications}, publisher = {Springer Nature}, url = {https://doi.org/10.1038/s41467-021-25914-8}, }