@article{Mutch_C-2022_94855,
title = {Performance status: A key factor in predicting mortality in the first wave of COVID-19 in South-East Scotland},
author = {Mutch, C. and Ross, D. and Bularga, A. and Cave, N. and Chase-Topping, M. and Anand, A. and Mills, N. and Koch, O. and Mackintosh, C. and Perry, M. and DataLoch COVID-19 Collaborative},
month = {aug},
year = {2022},
abstract = {Background: COVID-19 mortality risk factors have been established in large cohort studies; long-term mortality outcomes are less documented. Methods: We performed multivariable logistic regression to identify factors associated with in-patient mortality and intensive care unit (ICU) admission in symptomatic COVID-19 patients admitted to hospitals in South-East Scotland from 1st March to 30th June 2020. One-year mortality was reviewed. Results: Of 726 patients (median age 72; interquartile range: 58–83 years, 55% male), 104 (14%) required ICU admission and 199 (27%) died in hospital. A further 64 died between discharge and 30th June 2021 (36% overall 1-year mortality). Stepwise logistic regression identified age &gt;79 (odds ratio (OR), 4.77 (95% confidence interval (CI), 1.96–12.75)), male sex (OR, 1.83 (95% CI, 1.21–2.80)) and higher European Cooperative Oncology Group/World Health Organization performance status as associated with higher mortality risk. Discussion: Poor functional baseline was the predominant independent risk factor for mortality in COVID-19. More than one-third of individuals had died by 1 year following admission.},
journal = {Journal of the Royal College of Physicians of Edinburgh},
publisher = {SAGE Publications},
url = {https://doi.org/10.1177/14782715221120137},
}
