TY - JOUR
AU - The OpenSAFELY Collaborative
AU - Zheng, Bang
AU - Campbell, Jacqueline
AU - Carr, Edward J.
AU - Tazare, John
AU - Nab, Linda
AU - Mahalingasivam, Viyaasan
AU - Mehrkar, Amir
AU - Santhakumaran, Shalini
AU - Steenkamp, Retha
AU - Loud, Fiona
AU - Lyon, Susan
AU - Scanlon, Miranda
AU - Hulme, William
AU - Green, Amelia C.A.
AU - Curtis, Helen J.
AU - Fisher, Louis
AU - Parker, Edward
AU - Goldacre, Ben
AU - Douglas, Ian J.
AU - Evans, Stephen J.W.
AU - Mackenna, Brian
AU - Bell, Samira
AU - Tomlinson, Laurie A.
AU - Nitsch, Dorothea
AU - LH&W NCS (or CONVALESCENCE) Collaborative
PY - 2022
DA - December
TI - Comparative effectiveness of sotrovimab and molnupiravir for preventing severe COVID-19 outcomes in non-hospitalised patients on kidney replacement therapy: observational cohort study using the OpenSAFELY-UKRR linked platform and SRR database [pre-print]
JO - medRxiv
DO - https://doi.org/10.1101/2022.12.02.22283049
AB - BackgroundPatients on kidney replacement therapy (KRT; dialysis and kidney transplantation) are at the highest risk of severe outcomes from COVID-19. Due to limited inclusion of patients on KRT in clinical trials, information is limited on the effectiveness of sotrovimab (a neutralising monoclonal antibody). We sought to address this by comparing its effectiveness against molnupiravir (an antiviral) in preventing severe COVID-19 outcomes in non-hospitalised adults with symptomatic COVID-19.
PB - medRxiv
UR - https://publichealthscotland.scot/id/111561
KW - Coronavirus (COVID-19)
ER