TY - JOUR
AU - Bahadur, Gulam
AU - Acharya, Santanu
AU - Muneer, Asif
AU - Huirne, Judith
AU - Łukaszuk, Mariusz
AU - Doreski, Pablo Alexis
AU - Homburg, Roy
PY - 2020
DA - September
TI - SARS-CoV-2: diagnostic and design conundrums in the context of male factor infertility
JO - Reproductive BioMedicine Online
EP - 3369
VL - 41
IS - 3
DO - http://dx.doi.org/10.1016/j.rbmo.2020.05.014
AB - The question of whether SARS-CoV-2 (severe acute respiratory syndrome-related coronavirus-2 [SARS-CoV-2], leading to the COVID-19 infection) can be harboured in the testes and/or semen is currently unanswered. It is essential to understand the limitations of both antibody and real-time PCR tests in interpreting SARS-CoV-2 data in relation to analyses of semen and testicular tissue without appropriate controls. This article critically analyses the evidence so far on this, and the possible implications. The limitations of diagnostic tests in both sampling and testing methodologies, their validation and their relevance in interpreting data are also highlighted.
PB - Elsevier
UR - http://eprints.gla.ac.uk/227396/
KW - Coronavirus (COVID-19)
ER