TY - JOUR
AU - Morrow, Andrew J.
AU - Sykes, Robert
AU - Saleh, Merna
AU - Zahra, Baryab
AU - MacIntosh, Alasdair
AU - Kamdar, Anna
AU - Bagot, Catherine
AU - Bayes, Hannah K.
AU - Blyth, Kevin G.
AU - Bulluck, Heerajnarain
AU - Carrick, David
AU - Church, Colin
AU - Corcoran, David
AU - Findlay, Iain
AU - Gibson, Vivienne B.
AU - Gillespie, Lynsey
AU - Grieve, Douglas
AU - Hall Barrientos, Pauline
AU - Ho, Antonia
AU - Lang, Ninian N.
AU - Lowe, David J.
AU - Lennie, Vera
AU - Macfarlane, Peter W.
AU - Mayne, Kaitlin J.
AU - Mark, Patrick B.
AU - McConnachie, Alex
AU - McGeoch, Ross
AU - Nordin, Sabrina
AU - Payne, Alexander
AU - Rankin, Alastair J.
AU - Robertson, Keith E.
AU - Ryan, Nicola
AU - Roditi, Giles
AU - Sattar, Naveed
AU - Stobo, David
AU - Allwood-Spiers, Sarah
AU - Touyz, Rhian M.
AU - Veldtman, Gruschen
AU - Weeden, Sarah
AU - Weir, Robin A.
AU - Watkins, Stuart
AU - Welsh, Paul
AU - Mangion, Kenneth
AU - Berry, Colin
PY - 2024
DA - February
TI - Socioeconomic deprivation and illness trajectory in the Scottish population after COVID-19 hospitalization
JO - Communications Medicine
VL - 4
DO - https://doi.org/10.1038/s43856-024-00455-5
AB - Background The associations between deprivation and illness trajectory after hospitalisation for coronavirus disease-19 (COVID-19) are uncertain. Methods A prospective, multicentre cohort study was conducted on post-COVID-19 patients, enrolled either in-hospital or shortly post-discharge. Two evaluations were carried out: an initial assessment and a follow-up at 28–60 days post-discharge. The study encompassed research blood tests, patient-reported outcome measures, and multisystem imaging (including chest computed tomography (CT) with pulmonary and coronary angiography, cardiovascular and renal magnetic resonance imaging). Primary and secondary outcomes were analysed in relation to socioeconomic status, using the Scottish Index of Multiple Deprivation (SIMD). The EQ-5D-5L, Brief Illness Perception Questionnaire (BIPQ), Patient Health Questionnaire-4 (PHQ-4) for Anxiety and Depression, and the Duke Activity Status Index (DASI) were used to assess health status. Results Of the 252 enrolled patients (mean age 55.0 ± 12.0 years; 40% female; 23% with diabetes), deprivation status was linked with increased BMI and diabetes prevalence. 186 (74%) returned for the follow-up. Within this group, findings indicated associations between deprivation and lung abnormalities (p = 0.0085), coronary artery disease (p = 0.0128), and renal inflammation (p = 0.0421). Furthermore, patients with higher deprivation exhibited worse scores in health-related quality of life (EQ-5D-5L, p = 0.0084), illness perception (BIPQ, p = 0.0004), anxiety and depression levels (PHQ-4, p = 0.0038), and diminished physical activity (DASI, p = 0.002). At the 3-month mark, those with greater deprivation showed a higher frequency of referrals to secondary care due to ongoing COVID-19 symptoms (p = 0.0438). However, clinical outcomes were not influenced by deprivation. Conclusions In a post-hospital COVID-19 population, socioeconomic deprivation was associated with impaired health status and secondary care episodes. Deprivation influences illness trajectory after COVID-19.
PB - Springer Nature
UR - https://eprints.gla.ac.uk/320031/
KW - Coronavirus (COVID-19)
KW - Socioeconomic factors
KW - Hospital care
ER