TY - JOUR
AU - Mungroo, Mohammad Ridwane
AU - Khan, Naveed Ahmed
AU - Siddiqui, Ruqaiyyah
PY - 2020
DA - April
TI - Novel Coronavirus: Current Understanding of Clinical Features, Diagnosis, Pathogenesis, and Treatment Options
JO - Pathogens
VL - 9
IS - 4
DO - https://doi.org/10.3390/pathogens9040297
AB - Since December 2019, coronavirus disease 2019 (COVID-19) caused by severe acuterespiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in devastating consequencesworldwide and infected more than 350,000 individuals and killed more than 16,000 people.SARS-CoV-2 is the seventh member of the coronavirus family to affect humans. Symptoms ofCOVID-19 include fever (88%), cough (68%), vomiting (5%) and diarrhoea (3.7%), and transmissionof SARS-CoV-2 is thought to occur from human to human via respiratory secretions released by theinfected individuals when coughing and sneezing. COVID-19 can be detected through computedtomography scans and confirmed through molecular diagnostics tools such as polymerase chainreaction. Currently, there are no effective treatments against SARS-CoV-2, hence antiviral drugshave been used to reduce the development of respiratory complications by reducing viral load.The purpose of this review is to provide a comprehensive update on the pathogenesis, clinical aspects,diagnosis, challenges and treatment of SARS-CoV-2 infections.
PB - MDPI
UR - https://researchportal.hw.ac.uk/en/publications/a05125f9-888c-4a45-aebd-ada208c25f77
KW - Coronavirus (COVID-19)
ER