TY - JOUR
AU - Farouq, Mohammed A.H.
AU - Al Qaraghuli, Mohammed M.
AU - Kubiak-Ossowska, Karina
AU - Ferro, Valerie A.
AU - Mulheran, Paul A.
PY - 2021
DA - April
TI - Biomolecular interactions with nanoparticles : applications for COVID-19
JO - Current Opinion in Colloid & Interface Science
VL - 54
DO - https://doi.org/10.1016/j.cocis.2021.101461
AB - Nanoparticles are small particles sized 1–100 nm, which have a large surface-to-volume ratio, allowing efficient adsorption of drugs, proteins, and other chemical compounds. Consequently, functionalized nanoparticles have potential diagnostic and therapeutic applications. A variety of nanoparticles have been studied, including those constructed from inorganic materials, biopolymers, and lipids. In this review, we focus on recent work targeting the severe acute respiratory syndrome coronavirus 2 virus that causes coronavirus disease (COVID-19). Understanding the interactions between coronavirus-specific proteins (such as the spike protein and its host cell receptor angiotensin-converting enzyme 2) with different nanoparticles paves the way to the development of new therapeutics and diagnostics that are urgently needed for the fight against COVID-19, and indeed for related future viral threats that may emerge.
PB - Elsevier
UR - https://strathprints.strath.ac.uk/76238/
KW - Coronavirus (COVID-19)
ER