TY - JOUR AU - Al-Jarallah, Mohammed AU - Rajan, Rajesh AU - Al Saber, Ahmad R. AU - Pan, Jiazhu AU - T.Al-Sultan, Ahmad AU - Abdelnaby, Hassan AU - Alroomi, Moudhi AU - Dashti, Raja AU - Aboelhassan, Wael AU - Almutairi, Farah AU - Abdullah, Mohammed AU - Alotaibi, Naser AU - Al Saleh, Mohammad AU - AlNasrallah, Noor AU - Al-Bader, Bader AU - Malhas, Haya AU - Ramadhan, Maryam AU - Hamza, Mahdy AU - Zhanna, Kobalava D. PY - 2021 DA - May TI - In-hospital mortality in SARS-CoV-2 stratified by hemoglobin levels : a retrospective study JO - eJHaem EP - 1016 VL - 193 IS - 5 DO - https://doi.org/10.1002/jha2.195 AB - This study is to estimate in-hospital mortality in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) patients stratified by hemoglobin (Hb) level. Patients were stratified according to hemoglobin level into two groups, that is, Hb <100 g/L and Hb >100 g/L. A total of 6931 patients were included. Of these, 6377 (92%) patients had hemoglobin levels >100 g/L. The mean age was 44 ± 17 years, and 66% of the patients were males. The median length of overall hospital stay was 13 days [2; 31]. The remaining 554 (8%) patients had a hemoglobin level <100 g/L. Overall mortality was 176 patients (2.54%) but was significantly higher in the group with hemoglobin levels <100 g/L (124, 22.4%) than in the group with hemoglobin levels >100 g/L (52, 0.82%). Risk factors associated with increased mortality were determined by multi- variate analysis. The Kaplan-Meier survival analysis showed hemoglobin as a predictor of mortality. Cox proportional hazards regression coefficients for hemoglobin for the HB ≤ 100 category of hemoglobin were significant, B = 2.79, SE = 0.17, and HR = 16.34, p < 0.001. Multivariate logistic regression showed Hb < 100 g/L had a higher cumu- lative all-cause in-hospital mortality (22.4% vs. 0.8%; adjusted odds ratio [aOR], 0.33; 95% [CI]: [0.20–0.55]; p < 0.001). In this study, hemoglobin levels <100 g/L were found to be an independent predictor of in-hospital mortality. PB - British Society for Haematology PB - Wiley UR - https://strathprints.strath.ac.uk/76351/ KW - Coronavirus (COVID-19) KW - Hospital care ER