TY - JOUR
AU - Adeloye, Davies
AU - Elneima, Omer
AU - Daines, Luke
AU - Poinasamy, Krisnah
AU - Quint, Jennifer K.
AU - Walker, Samantha
AU - Brightling, Christopher E.
AU - Siddiqui, Salman
AU - Hurst, John R.
AU - Chalmers, James D.
AU - Pfeffer, Paul E.
AU - Novotny, Petr
AU - Drake, Thomas M.
AU - Heaney, Liam G.
AU - Rudan, Igor
AU - Sheikh, Aziz
AU - De Soyza, Anthony
PY - 2021
DA - August
TI - The long-term sequelae of COVID-19: an international consensus on research priorities for patients with pre-existing and new-onset airways disease
JO - The Lancet Respiratory Medicine
DO - https://doi.org/10.1016/S2213-2600(21)00286-1
AB - Persistent ill health after acute COVID-19-referred to as long COVID, the post-acute COVID-19 syndrome, or the post-COVID-19 condition-has emerged as a major concern. We undertook an international consensus exercise to identify research priorities with the aim of understanding the long-term effects of acute COVID-19, with a focus on people with pre-existing airways disease and the occurrence of new-onset airways disease and associated symptoms. 202 international experts were invited to submit a minimum of three research ideas. After a two-phase internal review process, a final list of 98 research topics was scored by 48 experts. Patients with pre-existing or post-COVID-19 airways disease contributed to the exercise by weighting selected criteria. The highest-ranked research idea focused on investigation of the relationship between prognostic scores at hospital admission and morbidity at 3 months and 12 months after hospital discharge in patients with and without pre-existing airways disease. High priority was also assigned to comparisons of the prevalence and severity of post-COVID-19 fatigue, sarcopenia, anxiety, depression, and risk of future cardiovascular complications in patients with and without pre-existing airways disease. Our approach has enabled development of a set of priorities that could inform future research studies and funding decisions. This prioritisation process could also be adapted to other, non-respiratory aspects of long COVID.
PB - Elsevier
UR - https://discovery.dundee.ac.uk/en/publications/abaf5792-54a3-4fda-9a28-a73ded820c4a
KW - Coronavirus (COVID-19)
ER