TY - JOUR AU - Solís Arce, Julio S. AU - Warren, Shana S. AU - Meriggi, Niccolò F. AU - Scacco, Alexandra AU - McMurry, Nina AU - Voors, Maarten AU - Syunyaev, Georgiy AU - Malik, Amyn A. AU - Aboutajdine, Samya AU - Adeojo, Opeyemi AU - Anigo, Deborah AU - Armand, Alex AU - Asad, Saher AU - Atyera, Martin AU - Augsburg, Britta AU - Awasthi, Manisha AU - Ayesiga, Gloria Eden AU - Bancalari, Antonella AU - Björkman Nyqvist, Martina AU - Borisova, Ekaterina AU - Bosancianu, Constantin Manuel AU - Cabra García, Magarita Rosa AU - Cheema, Ali AU - Collins, Elliott AU - Cuccaro, Filippo AU - Farooqi, Ahsan Zia AU - Fatima, Tatheer AU - Fracchia, Mattia AU - Galindo Soria, Mery Len AU - Guariso, Andrea AU - Hasanain, Ali AU - Jaramillo, Sofía AU - Kallon, Sellu AU - Kamwesigye, Anthony AU - Kharel, Arjun AU - Kreps, Sarah AU - Levine, Madison AU - Littman, Rebecca AU - Malik, Mohammad AU - Manirabaruta, Gisele AU - Mfura, Jean Léodomir Habarimana AU - Momoh, Fatoma AU - Mucauque, Alberto AU - Mussa, Imamo AU - Nsabimana, Jean Aime AU - Obara, Isaac AU - Otálora, María Juliana AU - Ouédraogo, Béchir Wendemi AU - Pare, Touba Bakary AU - Platas, Melina R. AU - Polanco, Laura AU - Qureshi, Javaeria Ashraf AU - Raheem, Mariam AU - Ramakrishna, Vasudha AU - Rendrá, Ismail AU - Shah, Taimur AU - Shaked, Sarene Eyla AU - Shapiro, Jacob N. AU - Svensson, Jakob AU - Tariq, Ahsan AU - Tchibozo, Achille Mignondo AU - Tiwana, Hamid Ali AU - Trivedi, Bhartendu AU - Vernot, Corey AU - Vicente, Pedro C. AU - Weissinger, Laurin B. AU - Zafar, Basit AU - Zhang, Baobao AU - Karlan, Dean AU - Callen, Michael AU - Teachout, Matthieu AU - Humphreys, Macartan AU - Mobarak, Ahmed Mushfiq AU - Omer, Saad B. PY - 2021 DA - July TI - COVID-19 vaccine acceptance and hesitancy in low- and middle-income countries JO - Nature Medicine EP - 1394 VL - 27 DO - https://doi.org/10.1038/s41591-021-01454-y AB - Widespread acceptance of COVID-19 vaccines is crucial for achieving sufficient immunization coverage to end the global pandemic, yet few studies have investigated COVID-19 vaccination attitudes in lower-income countries, where large-scale vaccination is just beginning. We analyze COVID-19 vaccine acceptance across 15 survey samples covering 10 low- and middle-income countries (LMICs) in Asia, Africa and South America, Russia (an upper-middle-income country) and the United States, including a total of 44,260 individuals. We find considerably higher willingness to take a COVID-19 vaccine in our LMIC samples (mean 80.3%; median 78%; range 30.1 percentage points) compared with the United States (mean 64.6%) and Russia (mean 30.4%). Vaccine acceptance in LMICs is primarily explained by an interest in personal protection against COVID-19, while concern about side effects is the most common reason for hesitancy. Health workers are the most trusted sources of guidance about COVID-19 vaccines. Evidence from this sample of LMICs suggests that prioritizing vaccine distribution to the Global South should yield high returns in advancing global immunization coverage. Vaccination campaigns should focus on translating the high levels of stated acceptance into actual uptake. Messages highlighting vaccine efficacy and safety, delivered by healthcare workers, could be effective for addressing any remaining hesitancy in the analyzed LMICs. PB - Springer Nature UR - http://hdl.handle.net/10023/23640 KW - Coronavirus (COVID-19) ER