TY - JOUR AU - Nadim, Mitra K. AU - Forni, Lui G. AU - Mehta, Ravindra L. AU - Connor, Michael J. AU - Liu, Kathleen D. AU - Ostermann, Marlies AU - Rimmelé, Thomas AU - Zarbock, Alexander AU - Bell, Samira AU - Bihorac, Azra AU - Cantaluppi, Vincenzo AU - Hoste, Eric AU - Husain-Syed, Faeq AU - Germain, Michael J. AU - Goldstein, Stuart L. AU - Gupta, Shruti AU - Joannidis, Michael AU - Kashani, Kianoush AU - Koyner, Jay L. AU - Legrand, Matthieu AU - Lumlertgul, Nuttha AU - Mohan, Sumit AU - Pannu, Neesh AU - Peng, Zhiyong AU - Perez-Fernandez, Xose L. AU - Pickkers, Peter AU - Prowle, John AU - Reis, Thiago AU - Srisawat, Nattachai AU - Tolwani, Ashita AU - Vijayan, Anitha AU - Villa, Gianluca AU - Yang, Li AU - Ronco, Claudio AU - Kellum, John A. PY - 2020 DA - December TI - COVID-19-associated acute kidney injury: Consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup JO - Nature Reviews Nephrology EP - 767 VL - 16 DO - https://doi.org/10.1038/s41581-020-00356-5 AB - Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT; also known as kidney replacement therapy). COVID-19-associated AKI (COVID-19 AKI) is associated with high mortality and serves as an independent risk factor for all-cause in-hospital death in patients with COVID-19. The pathophysiology and mechanisms of AKI in patients with COVID-19 have not been fully elucidated and seem to be multifactorial, in keeping with the pathophysiology of AKI in other patients who are critically ill. Little is known about the prevention and management of COVID-19 AKI. The emergence of regional ‘surges’ in COVID-19 cases can limit hospital resources, including dialysis availability and supplies; thus, careful daily assessment of available resources is needed. In this Consensus Statement, the Acute Disease Quality Initiative provides recommendations for the diagnosis, prevention and management of COVID-19 AKI based on current literature. We also make recommendations for areas of future research, which are aimed at improving understanding of the underlying processes and improving outcomes for patients with COVID-19 AKI. PB - Springer Nature UR - https://discovery.dundee.ac.uk/en/publications/40e3efaa-9516-489f-be94-1a191d985da3 KW - Coronavirus (COVID-19) ER