TY - JOUR AU - Burn, Edward AU - You, Seng Chan AU - Sena, Anthony G. AU - Kostka, Kristin AU - Abedtash, Hamed AU - Abrahão, Maria Tereza Fernandes AU - Alberga, Amanda AU - Alghoul, Heba AU - Alser, Osaid AU - Alshammari, Thamir M. AU - Aragón, María AU - Areia, Carlos AU - Banda, Juan M. AU - Cho, Jaehyeong AU - Culhane, Aedín C. AU - Davydov, Alexander AU - DeFalco, Frank J. AU - Duarte-Salles, Talita AU - DuVall, Scott L. AU - Falconer, Thomas AU - Fernández-Bertolín, Sergio AU - Gao, Weihua AU - Golozar, Asieh AU - Hardin, Jill AU - Hripcsak, George AU - Huser, Vojtech AU - Jeon, Hokyun AU - Jing, Yonghua AU - Jung, Chi Young AU - Kaas-Hansen, Benjamin Skov AU - Kaduk, Denys AU - Kent, Seamus AU - Kim, Yeesuk AU - Kolovos, Spyros AU - Lane, Jennifer C. E. AU - Lee, Hyejin AU - Lynch, Kristine E. AU - Makadia, Rupa AU - Matheny, Michael E. AU - Mehta, Paras P. AU - Morales, Daniel R. AU - Natarajan, Karthik AU - Nyberg, Fredrik AU - Ostropolets, Anna AU - Park, Rae Woong AU - Park, Jimyung AU - Posada, Jose D. AU - Prats-Uribe, Albert AU - Rao, Gowtham A. AU - Reich, Christian G. AU - Rho, Yeunsook AU - Rijnbeek, Peter AU - Schilling, Lisa M. AU - Schuemie, Martijn AU - Shah, Nigam H. AU - Shoaibi, Azza AU - Song, Seokyoung AU - Spotnitz, Matthew AU - Suchard, Marc A. AU - Swerdel, Joel N. AU - Vizcaya, David AU - Volpe, Salvatore AU - Wen, Haini AU - Williams, Andrew E. AU - Yimer, Belay B AU - Zhang, Lin AU - Zhuk, Oleg AU - Prieto-Alhambra, Daniel AU - Ryan, Patrick PY - 2020 DA - December TI - Deep phenotyping of 34,128 adult patients hospitalised with COVID-19 in an international network study JO - Nature Communications VL - 11 DO - https://doi.org/10.1038/s41467-020-18849-z AB - Comorbid conditions appear to be common among individuals hospitalised with coronavirus disease 2019 (COVID-19) but estimates of prevalence vary and little is known about the prior medication use of patients. Here, we describe the characteristics of adults hospitalised with COVID-19 and compare them with influenza patients. We include 34,128 (US: 8362, South Korea: 7341, Spain: 18,425) COVID-19 patients, summarising between 4811 and 11,643 unique aggregate characteristics. COVID-19 patients have been majority male in the US and Spain, but predominantly female in South Korea. Age profiles vary across data sources. Compared to 84,585 individuals hospitalised with influenza in 2014-19, COVID-19 patients have more typically been male, younger, and with fewer comorbidities and lower medication use. While protecting groups vulnerable to influenza is likely a useful starting point in the response to COVID-19, strategies will likely need to be broadened to reflect the particular characteristics of individuals being hospitalised with COVID-19. PB - Springer Nature UR - https://discovery.dundee.ac.uk/en/publications/d91a3b0b-6022-40e7-a5f4-f54778b638fb KW - Coronavirus (COVID-19) KW - Hospital care ER