TY - JOUR
AU - Viana, Raquel
AU - Moyo, Sikhulile
AU - Amoako, Daniel G.
AU - Tegally, Houriiyah
AU - Scheepers, Cathrine
AU - Althaus, Christian L.
AU - Anyaneji, Ugochukwu J.
AU - Bester, Phillip A.
AU - Boni, Maciej F.
AU - Chand, Mohammed
AU - Choga, Wonderful T.
AU - Colquhoun, Rachel M.
AU - Davids, Michaela
AU - Deforche, Koen
AU - Doolabh, Deelan
AU - du Plessis, Louis
AU - Engelbrecht, Susan
AU - Everatt, Josie
AU - Giandhari, Jennifer
AU - Giovanetti, Marta
AU - Hardie, Diana
AU - Hill, Verity
AU - Hsiao, Nei-yuan
AU - Iranzadeh, Arash
AU - Ismail, Arshad
AU - Joseph, Charity
AU - Joseph, Rageema
AU - Koopile, Legodile
AU - Kosakovsky Pond, Sergei L.
AU - Kraemer, Moritz U.G.
AU - Kuate-Lere, Lesego
AU - Laguda-Akingba, Oluwakemi
AU - Lesetedi-Mafoko, Onalethatha
AU - Lessells, Richard J.
AU - Lockman, Shahin
AU - Lucaci, Alexander G.
AU - Maharaj, Arisha
AU - Mahlangu, Boitshoko
AU - Maponga, Tongai
AU - Mahlakwane, Kamela
AU - Makatini, Zinhle
AU - Marais, Gert
AU - Maruapula, Dorcas
AU - Masupu, Kereng
AU - Matshaba, Mogomotsi
AU - Mayaphi, Simnikiwe
AU - Mbhele, Nokuzola
AU - Mbulawa, Mpaphi B.
AU - Mendes, Adriano
AU - Mlisana, Koleka
AU - Mnguni, Anele
AU - Mohale, Thabo
AU - Moir, Monika
AU - Moruisi, Kgomotso
AU - Mosepele, Mosepele
AU - Motsatsi, Gerald
AU - Motswaledi, Modisa S.
AU - Mphoyakgosi, Thongbotho
AU - Msomi, Nokukhanya
AU - Mwangi, Peter N.
AU - Naidoo, Yeshnee
AU - Ntuli, Noxolo
AU - Nyaga, Martin M.
AU - Olubayo, Luicer
AU - Pillay, Sureshnee
AU - Radibe, Botshelo
AU - Ramphal, Yajna
AU - Ramphal, Upasana
AU - San, James E.
AU - Scott, Lesley
AU - Shapiro, Roger
AU - Singh, Lavanya
AU - Smith-Lawrence, Pamela
AU - Stevens, Wendy
AU - Strydom, Amy
AU - Subramoney, Kathleen
AU - Tebeila, Naume
AU - Tshiabuila, Derek
AU - Tsui, Joseph
AU - van Wyk, Stephanie
AU - Weaver, Steven
AU - Wibmer, Constantinos K.
AU - Wilkinson, Eduan
AU - Wolter, Nicole
AU - Zarebski, Alexander E.
AU - Zuze, Boitumelo
AU - Goedhals, Dominique
AU - Preiser, Wolfgang
AU - Treurnicht, Florette
AU - Venter, Marietje
AU - Williamson, Carolyn
AU - Pybus, Oliver G.
AU - Bhiman, Jinal N.
AU - Glass, Allison
AU - Martin, Darren P.
AU - Rambaut, Andrew
AU - Gaseitsiwe, Simani
AU - von Gottberg, Anne
AU - De Oliveira, Tulio
PY - 2022
DA - January
TI - Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa
JO - Nature
DO - https://doi.org/10.1038/s41586-022-04411-y
AB - The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) epidemic in southern Africa has been characterised by three distinct waves. The first was associated with a mix of SARS-CoV-2 lineages, whilst the second and third waves were driven by the Beta and Delta variants, respectively. In November 2021, genomic surveillance teams in South Africa and Botswana detected a new SARS-CoV-2 variant associated with a rapid resurgence of infections in Gauteng Province, South Africa. Within three days of the first genome being uploaded, it was designated a variant of concern (Omicron) by the World Health Organization and, within three weeks, had been identified in 87 countries. The Omicron variant is exceptional for carrying over 30 mutations in the spike glycoprotein, predicted to influence antibody neutralization and spike function. Here, we describe the genomic profile and early transmission dynamics of Omicron, highlighting the rapid spread in regions with high levels of population immunity.
PB - Springer Nature
UR - https://www.research.ed.ac.uk/en/publications/5636a3ae-20ec-479f-a5de-001a5494f6df
KW - Coronavirus (COVID-19)
ER