TY - JOUR
AU - Thompson, Ellen J.
AU - Williams, Dylan M.
AU - Walker, Alex J.
AU - Mitchell, Ruth E.
AU - Niedzwiedz, Claire L.
AU - Yang, Tiffany C.
AU - Huggins, Charlotte F.
AU - Kwong, Alex S.F.
AU - Silverwood, Richard J.
AU - Di Gessa, Giorgio
AU - Bowyer, Ruth C.E.
AU - Northstone, Kate
AU - Hou, Bo
AU - Green, Michael J.
AU - Dodgeon, Brian
AU - Doores, Katie J.
AU - Duncan, Emma L.
AU - Williams, Frances M. K.
AU - Steptoe, Andrew
AU - Porteous, David J.
AU - McEachan, Rosemary R. C.
AU - Tomlinson, Laurie
AU - Goldacre, Ben
AU - Patalay, Praveetha
AU - Ploubidis, George B.
AU - Katikireddi, Srinivasa Vittal
AU - Tilling, Kate
AU - Rentsch, Christopher T.
AU - Timpson, Nicholas J.
AU - Chaturvedi, Nishi
AU - Steves, Claire J.
PY - 2022
DA - June
TI - Long COVID burden and risk factors in 10 UK longitudinal studies and electronic health records
JO - Nature Communications
VL - 13
DO - http://dx.doi.org/10.1038/s41467-022-30836-0
AB - The frequency of, and risk factors for, long COVID are unclear among community-based individuals with a history of COVID-19. To elucidate the burden and possible causes of long COVID in the community, we coordinated analyses of survey data from 6907 individuals with self-reported COVID-19 from 10 UK longitudinal study (LS) samples and 1.1 million individuals with COVID-19 diagnostic codes in electronic healthcare records (EHR) collected by spring 2021. Proportions of presumed COVID-19 cases in LS reporting any symptoms for 12+ weeks ranged from 7.8% and 17% (with 1.2 to 4.8% reporting debilitating symptoms). Increasing age, female sex, white ethnicity, poor pre-pandemic general and mental health, overweight/obesity, and asthma were associated with prolonged symptoms in both LS and EHR data, but findings for other factors, such as cardio-metabolic parameters, were inconclusive.
PB - Springer Nature
UR - http://eprints.gla.ac.uk/274140/
KW - Coronavirus (COVID-19)
ER