TY - JOUR AU - Holmes, Edward C. AU - Goldstein, Stephen A. AU - Rasmussen, Angela L. AU - Robertson, David L. AU - Crits-Christoph, Alexander AU - Wertheim, Joel O. AU - Anthony, Simon J. AU - Barclay, Wendy S. AU - Boni, Maciej F. AU - Doherty, Peter C. AU - Farrar, Jeremy AU - Geoghegan, Jemma L. AU - Jiang, Xiaowei AU - Leibowitz, Julian L. AU - Neil, Stuart J.D. AU - Skern, Tim AU - Weiss, Susan R. AU - Worobey, Michael AU - Andersen, Kristian G. AU - Garry, Robert F. AU - Rambaut, Andrew PY - 2021 DA - September TI - The origins of SARS-CoV-2: A critical review JO - Cell EP - 4856 VL - 184 IS - 19 DO - https://doi.org/10.1016/j.cell.2021.08.017 AB - Since the first reports of a novel severe acute respiratory syndrome (SARS)-like coronavirus in December 2019 in Wuhan, China, there has been intense interest in understanding how severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in the human population. Recent debate has coalesced around two competing ideas: a “laboratory escape” scenario and zoonotic emergence. Here, we critically review the current scientific evidence that may help clarify the origin of SARS-CoV-2. PB - Elsevier UR - https://www.research.ed.ac.uk/en/publications/3b891afe-ada5-4c15-be97-f0c6956c751a KW - Coronavirus (COVID-19) ER