TY - JOUR
AU - Panovska-Griffiths, Jasmina
AU - Swallow, Ben
AU - Hinch, R.
AU - Cohen, Jonathan
AU - Rosenfield, K.
AU - Stuart, R.M.
AU - Ferretti, Luca
AU - di Lauro, F.
AU - Wymant, C.
AU - Izzo, A.
AU - Waites, William
AU - Viner, Russell
AU - Bonell, Chris
AU - Fraser, C.
AU - Klein, D.J.
AU - Kerr, C.C.
AU - The COVID-19 Genomics UK (COG-UK) Consortium
PY - 2022
DA - October
TI - Statistical and agent-based modelling of the transmissibility of different SARS-CoV-2 variants in England and impact of different interventions
JO - Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences
VL - 380
IS - 2233
DO - https://dx.doi.org/10.1098/rsta.2021.0315
AB - The English SARS-CoV-2 epidemic has been affected by the emergence of new viral variants such as B.1.177, Alpha and Delta, and changing restrictions. We used statistical models and the agent-based model Covasim, in June 2021, to estimate B.1.177 to be 20% more transmissible than the wild type, Alpha to be 50–80% more transmissible than B.1.177 and Delta to be 65–90% more transmissible than Alpha. Using these estimates in Covasim (calibrated 1 September 2020 to 20 June 2021), in June 2021, we found that due to the high transmissibility of Delta, resurgence in infections driven by the Delta variant would not be prevented, but would be strongly reduced by delaying the relaxation of restrictions by one month and with continued vaccination.  This article is part of the theme issue ‘Technical challenges of modelling real-life epidemics and examples of overcoming these’.
PB - The Royal Society
UR - http://eprints.gla.ac.uk/276963/
KW - Coronavirus (COVID-19)
ER