TY - JOUR
AU - Fish, Matthew
AU - Rynne, Jennifer
AU - Jennings, Aislinn
AU - Lam, C
AU - Lamikanra, Abigail A.
AU - Ratcliff, Jeremy
AU - Cellone-Trevelin, S
AU - Timms, E
AU - Jeriha, Jakob
AU - Tosi, I
AU - Pramanik, R
AU - Simmonds, P
AU - Seth, Sohan
AU - Williams, J
AU - Gordon, Anthony C.
AU - Knight, Julian C.
AU - Smith, D J
AU - Whalley, J
AU - Harrison, D
AU - Rowan, K
AU - Harvala, Heli
AU - Klenerman, Paul
AU - Estcourt, Lise J.
AU - Menon, David K.
AU - Roberts, D
AU - Shankar-Hari, Manu
AU - REMAP-CAP Immunoglobulin Domain UK Investigators
PY - 2022
DA - September
TI - Coronavirus disease 2019 subphenotypes and differential treatment response to convalescent plasma in critically ill adults: secondary analyses of a randomized clinical trial
JO - Intensive Care Medicine
DO - https://doi.org/10.1007/s00134-022-06869-w
AB - Purpose: Benefit from convalescent plasma therapy for coronavirus disease 2019 (COVID19) has been inconsistent in randomized clinical trials (RCTs) involving critically ill patients. As COVID-19 patients are immunologically heterogeneous, we hypothesized that immunologically similar COVID-19 subphenotypes may differ in their treatment responses to convalescent plasma and explain inconsistent findings between RCTs.
PB - Springer Nature
UR - https://www.research.ed.ac.uk/en/publications/a2b49cf6-5c2e-4c4f-8c2a-e4ffd6c3f1c4
KW - Coronavirus (COVID-19)
ER