TY - JOUR
AU - Rosengren, Annika
AU - Lundberg, Christina E.
AU - Söderberg, Mia
AU - Santosa, Ailiana
AU - Edqvist, Jon
AU - Lindgren, Martin
AU - Åberg, Maria
AU - Gisslén, Magnus
AU - Robertson, Josefina
AU - Cronie, Ottmar
AU - Sattar, Naveed
AU - Lagergren, Jesper
AU - Brandén, Maria
AU - Björk, Jonas
AU - Adiels, Martin
PY - 2022
DA - May
TI - Severe COVID‐19 in people 55 and older during the first year of the pandemic in Sweden
JO - Journal of Internal Medicine
EP - 653
VL - 292
IS - 4
DO - https://doi.org/10.1111/joim.13522
AB - Background: Exposure to many contacts is the main risk factor for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, while risk of serious disease and death is chiefly determined by old age and comorbidities. Relative and population-attributable fractions (PAFs) of multiple medical and social exposures for COVID-19 outcomes have not been evaluated among older adults. Objectives: We describe the effect of multiple exposures on the odds of testing positive for the virus and of severe disease (hospital care or death) and PAFs in Swedish citizens aged 55 years and above. Methods: We used national registers to follow all citizens aged 55 years and above with respect to (1) testing positive, (2) hospitalization, and (3) death between 31 January 2020 and 1 February 2021. Results: Of 3,410,241 persons, 156,017 (4.6%, mean age 68.3 years) tested positive for SARS-CoV-2, while 35,999 (1.1%, mean age 76.7 years) were hospitalized or died (12,384 deaths, 0.4%, mean age 84.0 years). Among the total cohort, the proportion living without home care or long-term care was 98.8% among persons aged 55–64 and 22.1% of those aged 95 and above. After multiple adjustment, home care and long-term care were associated with odds ratios of 7.9 (95% confidence interval [CI] 6.8–9.1) and 22.5 (95% CI 19.6–25.7) for mortality, with PAFs of 21.9% (95% CI 20.9–22.9) and 33.3% (95% CI 32.4–34.3), respectively. Conclusion: Among Swedish residents aged 55 years and above, those with home care or long-term care had markedly increased risk for COVID-19 death during the first year of the pandemic, with over 50% of deaths attributable to these factors.
PB - Wiley
UR - https://eprints.gla.ac.uk/272457/
KW - Coronavirus (COVID-19)
KW - Older people
ER