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Showing 106 results

Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer

Author

Wright, Derek W.; Harvey, William T.; Hughes, Joseph; Cox, MacGregor; Peacock, Thomas P.; Colquhoun, Rachel M.; Jackson, Ben; Orton, Richard J.; The COVID-19 Genomics UK (COG-UK) Consortium; Harrison, Ewan M. and 5 others

Source

Virus Evolution

Type

Journal article

Published

18 March 2022
Whole genome sequencing reveals host factors underlying critical Covid-19

Author

Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 69 others

Source

Nature

Type

Journal article

Published

07 March 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19:A case study in affinity predictions of interface variants

Author

MacGowan, Stuart A.; Barton, Michael Ian; Kutuzov, Mikhail; Dushek, Omer; van der Merwe, P. Anton; Barton, Geoffrey J.

Source

PLoS Computational Biology

Type

Journal article

Published

02 March 2022
Genomic assessment of quarantine measures to prevent SARS-CoV-2 importation and transmission

Author

Aggarwal, Dinesh; Page, Andrew J.; Schaefer, Ulf; Savva, George M.; Myers, Richard; Volz, Erik; Ellaby, Nicholas; Platt, Steven; Groves, Natalie; Gallagher, Eileen and 11 others

Source

Nature Communications

Type

Journal article

Published

23 February 2022
The SARS-CoV-2 Alpha variant caused increased clinical severity of disease in Scotland: a genomics-based prospective cohort analysis

Author

Pascall, David J.; Mollett, Guy; Vink, Elen; Shepherd, James G.; Williams, Thomas; Wastnedge, Elizabeth; Blacow, Rachel; Hughes, Joseph; Robertson, David L.; Lycett, Samantha J. and 24 others

Source

medRxiv

Type

Journal article

Published

21 February 2022
Publisher Correction: Characterising within-hospital SARS-CoV-2 transmission events using epidemiological and viral genomic data across two pandemic waves

Author

Lindsey, Benjamin B.; Villabona-Arenas, Ch Julian; Campbell, Finlay; Keeley, Alexander J.; Parker, Matthew D.; Shah, Dhruv R.; Parsons, Helena; Zhang, Peijun; Kakkar, Nishchay; Gallis, Marta and 18 others

Source

Nature Communications

Type

Journal article

Published

17 February 2022
Pango lineage designation and assignment using SARS-CoV-2 spike gene nucleotide sequences

Author

O'Toole, Áine Niamh; Pybus, Oliver G.; Abram, Michael E.; Kelly, Elizabeth J.; Rambaut, Andrew

Source

BMC Genomics

Type

Journal article

Published

11 February 2022
The SARS-CoV-2 Spike Protein Mutation Explorer: Using Visualisations and Interactivity for Improved Communication about Variants of Concern

Author

Iannucci, Sarah; Harvey, William; Hughes, Joseph; Robertson, David; Poyade, Matthieu; Hutchinson, Edward

Source

Microbiology Society Annual Conference 2022

Type

Conference item

Published

08 February 2022
Mutations that adapt SARS-CoV-2 to mink or ferret do not increase fitness in the human airway

Author

Zhou, Jie; Peacock, Thomas P.; Brown, Jonathan C.; Goldhill, Daniel H.; Elrefaey, Ahmed M.E.; Penrice-Randal, Rebekah; Cowton, Vanessa M.; De Lorenzo, Giuditta; Furnon, Wilhelm; Harvey, William T. and 19 others

Source

Cell Reports

Type

Journal article

Published

08 February 2022
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

Author

Aggarwal, Dinesh; Warne, Ben; Jahun, Aminu S.; Hamilton, William L.; Fieldman, Thomas; du Plessis, Louis; Hill, Verity; Blane, Beth; Watkins, Emmeline; Wright, Elizabeth and 713 others

Source

Nature Communications

Type

Journal article

Published

08 February 2022