Recent advances in biomedical, biosensor and clinical measurement devices for use in humans and the potential application of these technologies for the study of physiology and disease in wild animals

Abstract

The goal of achieving enhanced diagnosis and continuous monitoring ofhuman health has led to a vibrant, dynamic and well-funded field ofresearch in medical sensing and biosensor technologies. The field hasmany sub-disciplines which focus on different aspects of sensor science;engaging engineers, chemists, biochemists and clinicians, often in interdisci-plinary teams. The trends which dominate include the efforts to developeffective point of care tests and implantable/wearable technologies forearly diagnosis and continuous monitoring. This review will outline the cur-rent state of the art in a number of relevant fields, including: deviceengineering, chemistry, nanoscience and biomolecular detection and suggesthow these advances might be employed to develop effective systems formeasuring physiology, detecting infection and monitoring biomarkerstatus in wild animals. Special consideration is also given to the emergingthreat of antimicrobial resistance and in the light of the current SARS-CoV-2 outbreak, zoonotic infections. Both of these areas involve significantcrossover between animal and human health and are therefore well placedto seed technological developments with applicability to both human andanimal health and more generally, the reviewed technologies have signifi-cant potential to find use in the measurement of physiology in wild animals.

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DOI

https://doi.org/10.1098/rstb.2020.0228

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https://pureportal.strath.ac.uk/en/publications/recent-advances-in-biomedical-biosensor-and-clinical-measurement-