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Showing 8 results

Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A mendelian randomisation study

Author

Hamilton, Fergus W; Thomas, Matt; Arnold, David; Palmer, Tom; Moran, Ed; Mentzer, Alexander J; Maskell, Nick; Baillie, Kenneth; Summers, Charlotte; Hingorani, Aroon and 6 others

Source

PLoS Medicine

Type

Journal article

Published

30 January 2023
Brain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses

Author

Needham, Edward J.; Ren, Alexander L.; Digby, Richard J.; Norton, Emma J.; Ebrahimi, Soraya; Outtrim, Joanne G.; Chatfield, Doris A.; Manktelow, Anne E.; Leibowitz, Maya M.; Newcombe, Virginia F.J. and 30 others

Source

Brain

Type

Journal article

Published

06 September 2022
Redefining Critical Illness

Author

Maslove, David M; Tang, Benjamin; Shankar-Hari, Manu; Lawler, Patrick R; Angus, Derek C; Baillie, J Kenneth; Baron, Rebecca M; Bauer, Michael; Buchman, Timothy G; Calfee, Carolyn S and 29 others

Source

Nature Medicine

Type

Journal article

Published

17 June 2022
Whole genome sequencing reveals host factors underlying critical Covid-19

Author

Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 69 others

Source

Nature

Type

Journal article

Published

07 March 2022
Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study

Author

Hurst, Emma; Mellanby, Richard; Handel, Ian; Griffith, David M; Rossi, Adriano G.; Walsh, Timothy S.; Shankar-Hari, Manu; Dunning, Jake; Homer, Natalie Z M; Denham, Scott G and 13 others

Source

BMJ Open

Type

Journal article

Published

22 October 2021
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Author

Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent; Absil, Lara; Acker, Andrew; Adachi, Shingo; Adam, Elisabeth; Adrião, Diana; Ainscough, Kate; Ait Hssain, Ali and 1054 others

Source

Infection

Type

Journal article

Published

25 June 2021
Genetic mechanisms of critical illness in Covid-19

Author

Pairo-Castineira, Erola; Clohisey, Sara; Klaric, Lucija; Bretherick, Andrew D.; Rawlik, Konrad; Pasko, Dorota; Walker, Susan; Parkinson, Nicholas; Head Fourman, Max; Russell, Clark D. and 60 others

Source

Nature

Type

Journal article

Published

11 December 2020
Therapeutic blockade of granulocyte macrophage colony-stimulating factor in COVID-19-associated hyperinflammation: challenges and opportunities

Author

Mehta, Puja R.; Porter, Joanna C.; Manson, Jessica J.; Isaacs, John D.; Openshaw, Peter J.M.; McInnes, Iain B.; Summers, Charlotte; Chambers, Rachel C.

Source

Lancet Respiratory Medicine

Type

Journal article

Published

01 August 2020

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