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Showing 32 results

The SARS-CoV-2 Alpha variant caused increased clinical severity of disease in Scotland: a genomics-based prospective cohort analysis

Author

Pascall, David J.; Mollett, Guy; Vink, Elen; Shepherd, James G.; Williams, Thomas; Wastnedge, Elizabeth; Blacow, Rachel; Hughes, Joseph; Robertson, David L.; Lycett, Samantha J. and 24 others

Source

medRxiv

Type

Journal article

Published

21 February 2022
Genomic epidemiology of SARS-CoV-2 in a UK university identifies dynamics of transmission

Author

Aggarwal, Dinesh; Warne, Ben; Jahun, Aminu S.; Hamilton, William L.; Fieldman, Tom; du Plessis, Louis; Hill, Verity; Blane, Beth; Watkins, Emmeline; Wright, Elizabeth and 713 others

Source

Nature Communications

Type

Journal article

Published

08 February 2022
The hyper-transmissible SARS-CoV-2 Omicron variant exhibits significant antigenic change, vaccine escape and a switch in cell entry mechanism

Author

Willett, Brian J.; Grove, Joe; MacLean, Oscar A.; Wilkie, Craig; Logan, Nicola; de Lorenzo, Giuditta; Furnon, Wilhelm; Scott, Sam; Manali, Maria; Szemiel, Agnieszka and 25 others

Source

medRxiv

Type

Journal article

Published

26 January 2022
Genomic reconstruction of the SARS-CoV-2 epidemic in England

Author

Vöhringer, Harald S.; Sanderson, Theo; Sinnott, Matthew; de Maio, Nicola; Nguyen, Thuy; Goater, Richard; Schwach, Frank; Harrison, Ian; Hellewell, Joel; Ariani, Cristina V. and 923 others

Source

Nature

Type

Journal article

Published

16 December 2021
Elevated temperature inhibits SARS-CoV-2 replication in respiratory epithelium independently of IFN-mediated innate immune defences

Author

Herder, Vanessa; Dee, Kieran; Wojtus, Joanna K.; Epifano, Ilaria; Goldfarb, Daniel M.; Rozario, Christoforos; Gu, Quan; da Silva Filipe, Ana; Nomikou, Kyriaki; Nichols, Jenna and 12 others

Source

PLoS Biology

Type

Journal article

Published

01 December 2021
The Alpha variant was not associated with excess nosocomial SARS-CoV-2 infection in a multi-centre UK hospital study

Author

Boshier, Florencia A.T.; Venturini, Cristina; Stirrup, Oliver; Guerra-Assunção, José Afonso; Alcolea-Medina, Adela; Beckett, Angela H.; Byott, Matthew; Charalampous, Themoula; da Silva Filipe, Ana; Frampton, Dan and 35 others

Source

Journal of Infection

Type

Journal article

Published

02 October 2021
SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study

Author

Stirrup, Oliver; Boshier, Florencia A.T.; Venturini, Cristina; Guerra-Assunção, José Afonso; Alcolea-Medina, Adela; Beckett, Angela H.; Charalampous, Themoula; da Silva Filipe, Ana; Glaysher, Sharon; Khan, Tabassum and 33 others

Source

BMJ Open Respiratory Research

Type

Journal article

Published

20 September 2021
In vitro selection of Remdesivir resistance suggests evolutionary predictability of SARS-CoV-2

Author

Szemiel, Agnieszka; Merits, Andreas; Orton, Richard J.; MacLean, Oscar A.; Pinto, Rute Maria; Wickenhagen, Arthur; Lieber, Gauthier; Turnbull, Matthew L.; Wang, Sainan; Furnon, Wilhelm and 10 others

Source

PLoS Pathogens

Type

Journal article

Published

01 September 2021
The SARS-CoV-2 Alpha variant causes increased clinical severity of disease

Author

Pascall, David J.; Mollett, Guy; Bulteel, Naomi; Campbell, Robyn; Campbell, Alasdair; Clifford, Sarah; Davis, Christopher; da Silva Filipe, Ana; Fjodorova, Ludmila; Forrester, Ruth and 21 others

Type

Journal article

Published

24 August 2021
COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Author

Abdukahil, Sheryl Ann; Abe, Ryuzo; Abel, Laurent; Absil, Lara; Acker, Andrew; Adachi, Shingo; Adam, Elisabeth; Adrião, Diana; Ainscough, Kate; Ait Hssain, Ali and 1054 others

Source

Infection

Type

Journal article

Published

25 June 2021