- 20 May 2020
Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study
In this study we provide the first report of the characteristics, comorbidities,
laboratory and x-ray findings, and clinical outcomes in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected patients with pre-existing liver cirrhosis. The cause of death in most patients was respiratory failure rather than progression of liver disease. Lower numbers of blood lymphocytes and platelets, and higher bilirubin levels might represent indicators of poor outcome in this patient population.
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Qi, X., Liu, Y., Wang, J., Fallowfield, J., Wang, J., Li, X., Shi, J., Pan, H., Zou, S., Zhang, H., Chen, Z., Li, F., Luo, Y., Mei, M., Liu, H., Wang, Z., Li, J., Yang, H., Xiang, H., Li, X., Liu, T., Zheng, M., Liu, C., Huang, Y., Xu, D., Li, X., Kang, N., He, Q., Gu, Y., Zhang, G., Shao, C., Liu, D., Zhang, L., Li, X., Kawada, N., Jiang, Z., Wang, F., Xiong, B., Takehara, T. & Rockey, D. 2020, 'Clinical course and risk factors for mortality of COVID-19 patients with pre-existing cirrhosis: a multicentre cohort study', Gut, 70(2), pp. 433-436. https://doi.org/10.1136/gutjnl-2020-321666