- Published
- 13 November 2024
- Journal article
Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh
- Authors
-
- Source
- Virology Journal
Abstract
Background
Genomic epidemiology has helped reconstruct the global and regional movement of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, there is still a lack of understanding of SARS-CoV-2 spread in some of the world’s least developed countries (LDCs).
Methods
To begin to address this disparity, we studied the transmission dynamics of the virus in Bangladesh during the country’s first COVID-19 wave by analysing case reports and whole-genome sequences from all eight divisions of the country.
Results
We detected>50 virus introductions to the country during the period, including during a period of national lockdown. Additionally, through discrete phylogeographic analyses, we identified that geographical distance and population -density and/or -size influenced virus spatial dispersal in Bangladesh.
Conclusions
Overall, this study expands our knowledge of SARS-CoV-2 genomic epidemiology in Bangladesh, shedding light on crucial transmission characteristics within the country, while also acknowledging resemblances and differences to patterns observed in other nations.
Rights
This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
Cite as
Carnegie, L., McCrone, J., du Plessis, L., Hasan, M., Ali, M., Begum, R., Hassan, M., Islam, S., Rahman, M., Uddin, A., Sarker, M., Das, T., Hossain, M., I Khan, M., Razu, M., Akram, A., Arina, S., Hoque, E., Molla, M., Nafisaa, T., Angra, P., Rambaut, A., Pullan, S., Osman, K., Hoque, M., Biswas, P., Flora, M., Raghwani, J., Fournié, G., Samad, M. & Hill, S. 2024, 'Genomic epidemiology of early SARS-CoV-2 transmission dynamics in Bangladesh', Virology Journal, 21, article no: 291. https://doi.org/10.1186/s12985-024-02560-2