ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19

Authors: Delles, Christian;

Li, Hongliang;

Touyz, Rhian M.

Source: Clinical Science

Full text

: https://doi.org/10.1042/CS20200363

Abstract

Angiotensin converting enzyme 2 (ACE2) is the major enzyme responsible for conversion of Ang II into Ang-(1-7). It also acts as the receptor for severe acute respiratory syndrome (SARS)-coronavirus (CoV)-2, which causes Coronavirus Disease (COVID)-19. In recognition of the importance of ACE2 and to celebrate 20 years since its discovery, the journal will publish a focused issue on the basic science and (patho)physiological role of this multifunctional protein.

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Cite as

Delles, C., Li, H. & Touyz, R. 2020, 'ACE2 the Janus-faced protein – from cardiovascular protection to severe acute respiratory syndrome-coronavirus and COVID-19', Clinical Science, 134(7), pp. 747-750. https://doi.org/10.1042/CS20200363

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DOI: https://doi.org/10.1042/CS20200363

Repository URI: http://eprints.gla.ac.uk/213481/