Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021

Authors: de Gier, Brechje ;

Andeweg, Stijn;

Joosten, Rosa;

ter Schegget, Ronald;

Smorenburg, Naomi;

van de Kassteele, Jan;

Hahné, Susan J.M.;

van den Hof, Susan;

de Melker, Hester E.;

Knol, Mirjam J.

Source: Eurosurveillance

Full text

: https://doi.org/10.2807/1560-7917.ES.2021.26.31.2100640

Abstract

Several studies report high effectiveness of COVID-19 vaccines against SARS-CoV-2 infection and severe disease, however an important knowledge gap is the vaccine effectiveness against transmission (VET). We present estimates of the VET to household and other close contacts in the Netherlands, from February to May 2021, using contact monitoring data. The secondary attack rate among household contacts was lower for fully vaccinated than unvaccinated index cases (11% vs 31%), with an adjusted VET of 71% (95% confidence interval: 63-77).

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http://creativecommons.org/licenses/by/4.0/

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de Gier, B., Andeweg, S., Joosten, R., ter Schegget, R., Smorenburg, N., van de Kassteele, J., Hahné, S., van den Hof, S., de Melker, H. & Knol, M. 2021, 'Vaccine effectiveness against SARS-CoV-2 transmission and infections among household and other close contacts of confirmed cases, the Netherlands, February to May 2021', Eurosurveillance, 26(31), article no: 2100640.. https://doi.org/10.2807/1560-7917.ES.2021.26.31.2100640

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DOI: https://doi.org/10.2807/1560-7917.ES.2021.26.31.2100640

Repository URI: https://researchonline.gcu.ac.uk/en/publications/ce52e6cd-4064-4b49-92bd-ab557686d60c