Effectiveness of BNT162b2 mRNA vaccine third doses and previous infection in protecting against SARS-CoV-2 infections during the Delta and Omicron variant waves; the UK SIREN cohort study September 2021 to February 2022 [pre-print]

Authors: Hall, Victoria J. ;

Insalata, Ferdinando;

Foulkes, Sarah ;

Kirwan, Peter D. ;

Sparkes, Dominic;

Atti, Ana ;

Cole, Michelle J.;

De Lacy, Elen;

Price, Lesley;

Corrigan, Diane;

Brown, Colin S.;

Islam, Jasmin;

SIREN Study Group;

Charlett, Andre;

Hopkins, Susan

Source: medRxiv

Full text

: https://doi.org/10.1101/2023.05.22.23290197

Abstract

Third doses of COVID-19 vaccines were widely deployed following primary vaccine course waning and emergence of the Omicron-variant. We investigated protection from third-dose vaccines and previous infection against SARS-CoV-2 infection during Delta-variant and Omicron-variant (BA.1 & BA.2) waves in our frequently PCR-tested cohort of healthcare-workers.

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The copyright holder for this preprint is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. It is made available under a CC-BY-NC-ND 4.0 International license. http://creativecommons.org/licenses/by-nc-nd/4.0/

Cite as

Hall, V., Insalata, F., Foulkes, S., Kirwan, P., Sparkes, D., Atti, A., Cole, M., De Lacy, E., Price, L., Corrigan, D., Brown, C., Islam, J., SIREN Study Group, Charlett, A. & Hopkins, S. 2023, 'Effectiveness of BNT162b2 mRNA vaccine third doses and previous infection in protecting against SARS-CoV-2 infections during the Delta and Omicron variant waves; the UK SIREN cohort study September 2021 to February 2022 [pre-print]'. To be published in medRxiv [Preprint]. Available at: https://doi.org/10.1101/2023.05.22.23290197

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DOI: https://doi.org/10.1101/2023.05.22.23290197