Abstract

The DECOVID database contains harmonized pseudonymized electronic health record (EHR) data on all adult (≥18 years old) patients presenting to two large, digitally-mature centers in the United Kingdom between 1 January 2020 and 28 February 2021, with fol-low-up until at least 28 March 2021. The database was originally developed to support the COVID-19 response, but is now available via the PIONEER data hub for researchers to ex-plore a wide range of research questions, including exploratory analyses, risk factor as-sessment, prediction modeling, and comparative effectiveness studies. Raw data were ex-tracted from local EHRs and transformed into a standardized form (Observational Health Data Sciences and Informatics-Common Data Model version 5.3.1). The database includes 165,420 patients across 256,804 hospital presentations. For these patients, highly granular data are available including patient demographics; and longitudinal vital signs, physiol-ogy, treatments, laboratory findings, clinical diagnoses and outcomes. There are 10,030 patients with COVID-19 included, of whom 1472 died in hospital.

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This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Cite as

Avramescu, A., Bakewell, N., Birds, I., Bowler, L., Chung, S., Clifton, D., N Cohen, S., Constantine-Cooke, N., Daub, E., Davidson, S., Denaxas, S., Diaz-Ordaz, K., Feltbower, R., Gallier, S., Gardiner, S., Gasperoni, F., Green, R., Hall, M., Holmes, C., Hurst, J., Iles, M., Jorge, J., Karoune, E., Keogh, R., King, R., King, R., Klapaukh, R., Kouchaki, S., Lai, A., Lea, N., Leyrat, C., Li, K., Lilaonitkul, W., Lu, H., Lyons, T., Mallon, A., Manderson, A., Margaritella, N., Matteson, J., Morley, S., Nicholls, H., O'Reilly, M., Pagel, C., Palmer, E., Roberts, J., Roberts, T., Robertson, D., Robinson, J., Rockenschaub, P., Ruddle, R., Sapey, E., Santos, L., Gao Smith, F., Starr, C., Strickson, O., Su, L., Tackney, M., Thygesen, J., Torralbo, A., Turner, A., Vallejos, C., Wang, C., Whitaker, K., Whitehouse, T., Westhead, D., Keong Wong, W., Wu, Y., Yang, L., Zou, X., DECOVID Consortium, Aslett, L., Camilleri, M., Goudie, R., Kirk, P. & Soltan, A. 2025, 'DECOVID: A UK Two-Center Harmonized Database of Acute Care Electronic Health Records for COVID-19 Research', MDPI Applied Biosciences, 10(12), article no: 195. https://doi.org/10.3390/data10120195

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Last updated: 02 December 2025
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