Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease

Authors: Al-Wahaibi, Lamya H. ;

Mostafa, Ahmed;

Mostafa, Yaser A.;

Abou-Ghadir, Ola F.;

Abdelazeem, Ahmed H.;

Gouda, Ahmed M.;

Kutkat, Omnia;

Abo Shama, Noura M.;

Shehata, Mahmoud;

Gomaa, Hesham A.M.;

Abdelrahman, Mostafa H.;

Mohamed, Fatma A.M.;

Gu, Xuyuan;

Ali, Mohamed A.;

Trembleau, Laurent ;

Youssif, Bahaa G.M.

Source: Bioorganic Chemistry

Full text

: https://doi.org/10.1016/j.bioorg.2021.105363

Abstract

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The manuscript version is made available on the University of Aberdeen Repository under the CC-BY-NC-ND 4.0 license: https://creativecommons.org/licenses/by-nc-nd/4.0/.

Cite as

Al-Wahaibi, L., Mostafa, A., Mostafa, Y., Abou-Ghadir, O., Abdelazeem, A., Gouda, A., Kutkat, O., Abo Shama, N., Shehata, M., Gomaa, H., Abdelrahman, M., Mohamed, F., Gu, X., Ali, M., Trembleau, L. & Youssif, B. 2021, 'Discovery of novel oxazole-based macrocycles as anti-coronaviral agents targeting SARS-CoV-2 main protease', Bioorganic Chemistry, 116, article no: 105363. https://doi.org/10.1016/j.bioorg.2021.105363

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DOI: https://doi.org/10.1016/j.bioorg.2021.105363

Repository URI: https://hdl.handle.net/2164/19196