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Showing 141 results

Reprogrammed tracrRNAs enable repurposing of RNAs as crRNAs and sequence-specific RNA biosensors

Author

Liu, Yang; Pinto, Filipe; Wan, Xinyi; Yang, Zhugen; Peng, Shuguang; Li, Mengxi; Cooper, Jonathan M.; Xie, Zhen; French, Christopher E.; Wang, Baojun

Source

Nature Communications

Type

Journal article

Published

11 April 2022
Genetic landscape of the ACE2 coronavirus receptor

Author

Yang, Zhijian; MacDonald-Dunlop, Erin; Chen, Jiantao; Zhai, Ranran; Li, Ting; Richmond, Anne; Klaric, Lucija; Pirastu, Nicola; Ning, Zheng; Zheng, Chenqing and 59 others

Source

Circulation

Type

Journal article

Published

07 April 2022
Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function

Author

Martin, Darren P.; Lytras, Spyros; Lucaci, Alexander G.; Maier, Wolfgang; Grüning, Björn; Shank, Stephen D.; Weaver, Steven; MacLean, Oscar A.; Orton, Richard J.; Lemey, Philippe and 28 others

Source

Molecular Biology and Evolution

Type

Journal article

Published

01 April 2022
Efficient Screening of Long Oligonucleotides Against Hundred Thousands of SARS-CoV-2 Genome Sequences

Author

Weidmann, Manfred; Graf, Elena; Lichterfeld, Daniel; Abd El Wahed, Ahmed; Bekaert, Michaël

Source

Frontiers in Virology

Type

Journal article

Published

25 March 2022
Global mapping of RNA homodimers in living cells

Author

Gabryelska, Marta M.; Badrock, Andrew P.; Lau, Jian You; O'Keefe, Raymond T.; Crow, Janick J.; Kudla, Grzegorz

Source

Genome Research

Type

Journal article

Published

24 March 2022
Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer

Author

Wright, Derek W.; Harvey, William T.; Hughes, Joseph; Cox, MacGregor; Peacock, Thomas P.; Colquhoun, Rachel M.; Jackson, Ben; Orton, Richard J.; The COVID-19 Genomics UK (COG-UK) Consortium; Harrison, Ewen M. and 5 others

Source

Virus Evolution

Type

Journal article

Published

18 March 2022
Organ-specific or personalized treatment for COVID-19: rationale, evidence, and potential candidates

Author

Mousavi, Seyedeh Zahra; Rahmanian, Mojdeh; Sami, Ashkan

Source

Functional & Integrative Genomics

Type

Journal article

Published

15 March 2022
Whole-genome sequencing reveals host factors underlying critical COVID-19

Author

Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 46 others

Source

Nature

Type

Journal article

Published

07 March 2022
Whole genome sequencing reveals host factors underlying critical Covid-19

Author

Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 69 others

Source

Nature

Type

Journal article

Published

07 March 2022
Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19:A case study in affinity predictions of interface variants

Author

MacGowan, Stuart A.; Barton, Michael Ian; Kutuzov, Mikhail; Dushek, Omer; van der Merwe, P. Anton; Barton, Geoffrey J.

Source

PLoS Computational Biology

Type

Journal article

Published

02 March 2022