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Showing 9 results

GWAS and meta-analysis identifies 49 genetic variants underlying critical Covid-19

Author

Pairo-Castineira, Erola; Rawlik, Konrad; Bretherick, Andrew D.; Qi, Ting; Wu, Yang; Nassiri, Isar; McConkey, Glenn A.; Zechner, Marie; Klaric, Lucija; Griffiths, Fiona and 45 others

Source

Nature

Type

Journal article

Published

17 May 2023
An Inhaled Galectin-3 Inhibitor in COVID-19 Pneumonitis (DEFINE): A Phase Ib/IIa Randomised Controlled Trial

Author

Gaughan, Erin; Quinn, Tom M.; Mills, Andrew; Bruce, Annya; Antonelli, Jean; Mackinnon, Alison; Aslanis, Vassilios; Li, Feng; O'Connor, Richard A.; Boz, Cecilia and 29 others

Source

American Journal of Respiratory and Critical Care Medicine

Type

Journal article

Published

16 August 2022
Redefining Critical Illness

Author

Maslove, David M.; Tang, Benjamin; Shankar-Hari, Manu; Lawler, Patrick R; Angus, Derek C.; Baillie, J. Kenneth; Baron, Rebecca M.; Bauer, Michael; Buchman, Timothy G.; Calfee, Carolyn S. and 29 others

Source

Nature Medicine

Type

Journal article

Published

17 June 2022
Outcomes from COVID-19 Clinical Trials in Hospitalized Patients: Seeking the Truth That Matters

Author

Griffith, David; Walsh, Timothy

Source

American Journal of Respiratory and Critical Care Medicine

Type

Journal article

Published

24 May 2022
Whole genome sequencing reveals host factors underlying critical Covid-19

Author

Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 69 others

Source

Nature

Type

Journal article

Published

07 March 2022
Randomised Controlled Trial of Intravenous Nafamostat Mesylate in COVID pneumonitis: Phase 1b/2a Experimental Study to Investigate Safety, Pharmacokinetics and Pharmacodynamics

Author

Quinn, Tom M.; Gaughan, Erin; Bruce, Annya; Antonelli, Jean; O'Connor, Richard A.; Li, Feng; McNamara, Sarah; Koch, Oliver; Mackintosh, Claire L.; Dockrell, David H. and 29 others

Source

EBioMedicine

Type

Journal article

Published

10 February 2022
Recovery from Covid-19 critical illness: a secondary analysis of the ISARIC4C CCP-UK cohort study and the RECOVER trial

Author

Pauley, Ellen; Drake, Thomas M.; Sigfrid, Louise; Lone, Nazir I.; Harrison, Ewen M.; Baillie, J. Kenneth; Scott, Janet T.; Walsh, Timothy; Semple, Malcolm G.; Docherty, Annemarie B.

Source

Journal of the Intensive Care Society

Type

Journal article

Published

24 October 2021
Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study

Author

Hurst, Emma; Mellanby, Richard; Handel, Ian; Griffith, David; Rossi, Adriano G.; Walsh, Timothy; Shankar-Hari, Manu; Dunning, Jake; Homer, Natalie Z.M.; Denham, Scott G. and 13 others

Source

BMJ Open

Type

Journal article

Published

22 October 2021
Genetic mechanisms of critical illness in Covid-19

Author

Pairo-Castineira, Erola; Clohisey, Sara; Klaric, Lucija; Bretherick, Andrew D.; Rawlik, Konrad; Pasko, Dorota; Walker, Susan; Parkinson, Nicholas; Head Fourman, Max; Russell, Clark D. and 60 others

Source

Nature

Type

Journal article

Published

11 December 2020

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