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Showing 281 results

  • Investigating the impact of dipeptidyl peptidase-1 inhibition in humans using multi-omics

    Author
    Long, Merete B.; Gilmour, Amy; Hull, Rebecca C.; Giam, Yan Hui; Richardson, Hollian; Hughes, Chloe; Abo-Leyah, Hani; Keir, Holly R.; Dowey, Rebecca; Turton, Helena and 16 others
    Source
    Journal of Allergy and Clinical Immunology
    Type
    Journal article
    Published
    06 August 2025
  • PROS1 released by lung basal cells limits inflammation in epithelial and monocytes during SARS-CoV-2 infection

    Author
    Simakou, Theodoros; Szemiel, Agnieszka M.; MacDonald, Lucy; Kerr, Karen; Somma, Domenico; Diallo, Katy; Frew, Jack; Hardy, Olympia M.; Doohan, Marcus; Elmesmari, Aziza and 5 others
    Source
    Discovery Immunology
    Type
    Journal article
    Published
    05 August 2025
  • Label-Free Electrochemical Interleukin-6 Sensor Exploiting rGO-Ti3C2TxMXene Nanocomposites

    Author
    Gupta, Rohit; Kalkal, Ashish; Mandal, Priya; Paital, Diptiranjan; Brealey, David; Tiwari, Manish K.
    Source
    ACS Applied Materials and Interfaces
    Type
    Journal article
    Published
    24 July 2025
  • Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2

    Author
    Vaidergorn, Miguel M.; Purificação, Aline D.; Leite, Pedro I.P.; Silva-Mendonça, Sabrina; Silva, Wemenes J.L.; Silva, Daniel Gedder; Godoi, Bruna Fleck; Sacramento, Carolina Q.; Mattos, Mayara; Fintelman-Rodrigues, Natalia and 13 others
    Source
    European Journal of Medicinal Chemistry
    Type
    Journal article
    Published
    21 June 2025
  • Identification of undetected SARS-CoV-2 infections by clustering of Nucleocapsid antibody trajectories

    Author
    Zwerwer, Leslie R.; Pouwels, Koen B.; Walker, Ann Sarah; Eyre, David W.; Stroesser, Nicole; Matthews, Philippa C.; Wei, Jia; Diamond, Ian; Studley, Ruth; Taylor, Nick and 62 others
    Source
    Nature Communications
    Type
    Journal article
    Published
    14 May 2025
  • The DESTINIES Study: an online Delphi study to build international consensus on the medical conditions and procedures that confer immunosuppression and their respective COVID-19 risk profiles

    Author
    Leston, Meredith; Ordóñez-Mena, José M.; Joy, Mark; de Lusignan, Simon; Teh, Benjamin W.; de Groot, Ingrid; McInnes, Iain B.; El Sahly, Hana M.; Isaacs, John D.; Andersson, Monique and 12 others
    Source
    eClinicalMedicine
    Type
    Journal article
    Published
    04 May 2025
  • A viro-immunological model to characterize the antiviral effect of molnupiravir in SARS-CoV-2-infected outpatients: implication for treatment duration

    Author
    Nguyen, Bach Tran; Bertrand, Julie; Zhang, Shengyuan; Yu, Ly-Mee; Harris, Victoria Claire; Little, Paul; Breuer, Judith; Guedj, Jérémie; group, PANORAMIC study; Agyeman, Akosua A. and 3 others
    Source
    Journal of Infectious Diseases
    Type
    Journal article
    Published
    01 April 2025
  • Post-pandemic changes in population immunity have reduced the likelihood of emergence of zoonotic coronaviruses [pre-print]

    Author
    Imrie, Ryan M.; Bissett, Laura A.; Raveendran, Savitha; Manali, Maria; Amat, A.R.; Mojsiejczuk, Laura; Logan, Nicola; Park, Andrew; Baguelin, Marc; Viana, Mafalda and 2 others
    Source
    medRxiv
    Type
    Journal article
    Published
    17 March 2025
  • Comparative analysis of ACE2 mutations and their impact on SARS-CoV-2 susceptibility within diverse ethnic groups

    Author
    Shafique, Rabia; Zahra, Ambreen; Butt, Muhammad Hassan; Khan, Sultan Habibullah; Ali, Waqas Rafique; Arshad, Muhammad Imran; Shamim, Amen
    Source
    Journal of Biomolecular Structure and Dynamics
    Type
    Journal article
    Published
    10 March 2025
  • Post-Hospitalisation COVID-19 Rehabilitation (PHOSP-R): A randomised controlled trial of exercise-based rehabilitation

    Author
    Daynes, Enya; Evans, Rachael A.; Greening, Neil J.; Bishop, Nicolette C.; Yates, Tom A.; Lozano-Rojas, Daniel; Ntotsis, Kimon; Richardson, Matthew; Baldwin, Molly; Hamrouni, Malik and 31 others
    Source
    European Respiratory Journal
    Type
    Journal article
    Published
    20 February 2025
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