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Showing 141 results

  • Reprogrammed tracrRNAs enable repurposing of RNAs as crRNAs and sequence-specific RNA biosensors

    Author
    Liu, Yang; Pinto, Filipe; Wan, Xinyi; Yang, Zhugen; Peng, Shuguang; Li, Mengxi; Cooper, Jonathan M.; Xie, Zhen; French, Christopher E.; Wang, Baojun
    Source
    Nature Communications
    Type
    Journal article
    Published
    11 April 2022
  • Genetic landscape of the ACE2 coronavirus receptor

    Author
    Yang, Zhijian; MacDonald-Dunlop, Erin; Chen, Jiantao; Zhai, Ranran; Li, Ting; Richmond, Anne; Klaric, Lucija; Pirastu, Nicola; Ning, Zheng; Zheng, Chenqing and 59 others
    Source
    Circulation
    Type
    Journal article
    Published
    07 April 2022
  • Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA.1 that likely impact Spike function

    Author
    Martin, Darren P.; Lytras, Spyros; Lucaci, Alexander G.; Maier, Wolfgang; Grüning, Björn; Shank, Stephen D.; Weaver, Steven; MacLean, Oscar A.; Orton, Richard J.; Lemey, Philippe and 28 others
    Source
    Molecular Biology and Evolution
    Type
    Journal article
    Published
    01 April 2022
  • Efficient Screening of Long Oligonucleotides Against Hundred Thousands of SARS-CoV-2 Genome Sequences

    Author
    Weidmann, Manfred; Graf, Elena; Lichterfeld, Daniel; Abd El Wahed, Ahmed; Bekaert, Michaël
    Source
    Frontiers in Virology
    Type
    Journal article
    Published
    25 March 2022
  • Global mapping of RNA homodimers in living cells

    Author
    Gabryelska, Marta M.; Badrock, Andrew P.; Lau, Jian You; O'Keefe, Raymond T.; Crow, Janick J.; Kudla, Grzegorz
    Source
    Genome Research
    Type
    Journal article
    Published
    24 March 2022
  • Tracking SARS-CoV-2 mutations and variants through the COG-UK-Mutation Explorer

    Author
    Wright, Derek W.; Harvey, William T.; Hughes, Joseph; Cox, MacGregor; Peacock, Thomas P.; Colquhoun, Rachel M.; Jackson, Ben; Orton, Richard J.; The COVID-19 Genomics UK (COG-UK) Consortium; Harrison, Ewen M. and 5 others
    Source
    Virus Evolution
    Type
    Journal article
    Published
    18 March 2022
  • Organ-specific or personalized treatment for COVID-19: rationale, evidence, and potential candidates

    Author
    Mousavi, Seyedeh Zahra; Rahmanian, Mojdeh; Sami, Ashkan
    Source
    Functional & Integrative Genomics
    Type
    Journal article
    Published
    15 March 2022
  • Whole-genome sequencing reveals host factors underlying critical COVID-19

    Author
    Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 46 others
    Source
    Nature
    Type
    Journal article
    Published
    07 March 2022
  • Whole genome sequencing reveals host factors underlying critical Covid-19

    Author
    Kousathanas, Athanasios; Pairo-Castineira, Erola; Rawlik, Konrad; Stuckey, Alex; Odhams, Christopher A.; Walker, Susan; Russell, Clark D.; Malinauskas, Tomas; Wu, Yang; Millar, Jonathan E. and 69 others
    Source
    Nature
    Type
    Journal article
    Published
    07 March 2022
  • Missense variants in human ACE2 strongly affect binding to SARS-CoV-2 Spike providing a mechanism for ACE2 mediated genetic risk in Covid-19:A case study in affinity predictions of interface variants

    Author
    MacGowan, Stuart A.; Barton, Michael Ian; Kutuzov, Mikhail; Dushek, Omer; van der Merwe, P. Anton; Barton, Geoffrey J.
    Source
    PLoS Computational Biology
    Type
    Journal article
    Published
    02 March 2022
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