On 31 March 2022, the Scottish National Health Service (NHS) Greater Glasgow and Clyde (GGC) Health Board alerted Public Health Scotland (PHS) to five children aged 3–5 years presenting to the Royal Hospital for Children, Glasgow with severe hepatitis of unknown aetiology within a 3-week period. The typical number of cases of hepatitis of unknown aetiology across Scotland would be fewer than four per year.

This paper describes the initial investigation into the first Scottish cases and aims to raise awareness of this severe illness of unknown aetiology among young children.


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Marsh, K., Tayler, R., Pollock, L., Roy, K., Lakha, F., Ho, A., Henderson, D., Divala, T., Currie, S., Yirrell, D., Lockhart, M., Rossi, M. & Phin, N. 2022, 'Investigation into cases of hepatitis of unknown aetiology among young children, Scotland, 1 January 2022 to 12 April 2022', Eurosurveillance, 27(15). http://doi.org/10.2807/1560-7917.ES.2022.27.15.2200318

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Last updated: 16 June 2022
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