Molnupiravir plus usual care versus usual care alone as early treatment for adults with COVID-19 at increased risk of adverse outcomes (PANORAMIC): an open-label, platform-adaptive randomised controlled trial

Authors

Butler, Christopher C. ; 

Hobbs, F.D. Richard; 

Gbinigie, Oghenekome A.; 

Rahman, Najib M.; 

Hayward, Gail; 

Richards, Duncan B.; 

Dorward, Jienchi; 

Lowe, David M.; 

Standing, Joseph F. ; 

Breuer, Judith ; 

Khoo, Saye; 

Petrou, Stavros; 

Hood, Kerenza; 

Nguyen-Van-Tam, Jonathan S.; 

Patel, Mahendra G.; 

Saville, Benjamin R.; 

Marion, Joe; 

Ogburn, Emma; 

Allen, Julie; 

Rutter, Heather; 

Francis, Nick; 

Thomas, Nicholas P. B.; 

Evans, Philip; 

Dobson, Melissa; 

Madden, Tracie-Ann; 

Holmes, Jane; 

Harris, Victoria C.; 

Png, May Ee; 

Lown, Mark; 

van Hecke, Oliver; 

Detry, Michelle A.; 

Saunders, Christina T.; 

Fitzgerald, Mark; 

Berry, Nicholas S.; 

Mwandigha, Lazaro; 

Galal, Ushma; 

Mort, Sam; 

Jani, Bhautesh D. ; 

Hart, Nigel D.; 

Ahmed, Haroon; 

Butler, Daniel; 

McKenna, Micheal; 

Chalk, Jem; 

Lavallee, Layla; 

Hadley, Elizabeth; 

Cureton, Lucy; 

Benysek, Magdalena; 

Andersson, Monique; 

Coates, Maria; 

Barrett, Sarah; 

Bateman, Clare; 

Davies, Jennifer C.; 

Raymundo-Wood, Ivy; 

Ustianowski, Andrew; 

Carson-Stevens, Andrew; 

Yu, Ly-Mee; 

Little, Paul; 

Agyeman, Akosua A.; 

Ahmed, Tanveer; 

Allcock, Damien; 

Beltran-Martinez, Adrian; 

Benedict, Oluseye E.; 

Bird, Nigel; 

Brennan, Laura; 

Brown, Julianne R.; 

Burns, Gerard; 

Butler, Mike; 

Cheng, Zelda; 

Danson, Ruth; 

de Kare-Silver, Nigel; 

Dhasmana, Devesh; 

Dickson, Jon; 

Engamba, Serge; 

Fisher, Stacey; 

Fox, Robin; 

Frost, Eve; 

Gaunt, Richard; 

Ghosh, Sarit; 

Gilkar, Ishtiaq; 

Goodman, Anna L.; 

Granier, Steve; 

Howell, Aleksandra; 

Hussain, Iqbal; 

Hutchinson, Simon; 

Imlach, Marie; 

Irving, Greg; 

Jacobsen, Nicholas; 

Kennard, James; 

Khan, Umar F.; 

Knox, Kyle; 

Krasucki, Christopher; 

Law, Tom; 

Lee, Rem; 

Lester, Nicola; 

Lewis, David; 

Lunn, James; 

Mackintosh, Claire L.; 

Mathukia, Mehul; 

Moore, Patrick; 

Morton, Seb; 

Murphy, Daniel; 

Nally, Rhiannon; 

Ndukauba, Chinonso; 

Ogundapo, Olufunto; 

Okeke, Henry; 

Patel, Amit; 

Patel, Kavil; 

Penfold, Ruth; 

Poonian, Satveer; 

Popoola, Olajide; 

Pora, Alexander; 

Prasad, Vibhore; 

Prasad, Rishabh; 

Razzaq, Omair; 

Richardson, Scot; 

Royal, Simon; 

Safa, Afsana; 

Sehdev, Satash; 

Sevenoaks, Tamsin; 

Shah, Divya; 

Sheikh, Aadil; 

Short, Vanessa; 

Sidhu, Baljinder S.; 

Singh, Ivor; 

Soni, Yusuf; 

Thalasselis, Chris; 

Wilson, Pete; 

Wingfield, David; 

Wong, Michael; 

Woodall, Maximillian N. J.; 

Wooding, Nick; 

Woods, Sharon; 

Yong, Joanna; 

Yongblah, Francis; 

Zafar, Azhar

Source

The Lancet